(±)-Rotigotine

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Names

[ Name ]:
(±)-Rotigotine

[Synonym ]:
6-(Propyl(2-(2-thienyl)ethyl)amino)-5,6,7,8-tetrahydro-1-naphthalenol
6-{Propyl[2-(2-thienyl)ethyl]amino}-5,6,7,8-tetrahydro-1-naphthalenol
5-hydroxy-2-(N-n-propyl-N-2-ethylthienyl-amino)tetralin
1-Naphthalenol, 5,6,7,8-tetrahydro-6-[propyl[2-(2-thienyl)ethyl]amino]-
6-{propyl[2-(thiophen-2-yl)ethyl]amino}-5,6,7,8-tetrahydronaphthalen-1-ol
UNII:5QTR54Z0E1
rotigotine transdermal patch
N-0437
ent-Rotigotine
ROTIGOTINE, (±)-
1-Naphthalenol, 5,6,7,8-tetrahydro-6-(propyl(2-(2-thienyl)ethyl)amino)-
(-)-5,6,7,8-tetrahydro-6-[propyl[2-(thien-2-yl)ethyl]-amino]-1-naphthol
6-{Propyl[2-(2-thienyl)ethyl]amino}-5,6,7,8-tetrahydronaphthalen-1-ol
2-(N-propyl-N-(2-thiofuranyl)-2'-ethylamino)-5-hydroxy-1,2,3,4-tetrahydronaphthalene
[3H]-N 0437

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
470.1±45.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₉H₂₅NOS

[ Molecular Weight ]:
315.47

[ Flash Point ]:
238.1±28.7 °C

[ Exact Mass ]:
315.165680

[ PSA ]:
51.71000

[ LogP ]:
4.96

[ Vapour Pressure ]:
0.0±1.2 mmHg at 25°C

[ Index of Refraction ]:
1.611

Safety Information

[ HS Code ]:
2934999090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

2-(2-Thienyl)ethyl 4-methylbenzenesulfonate
rac-5,6,7,8-Tetrahydro-6-(propylamino)-1-naphthalenol
2-Thienylacetic acid
5-Methoxy-2-tetralone
2-PROPYLAMINO-5-METHOXYTETRALIN
(S)-5-METHOXY-N-PROPYL-N-(2-(THIOPHEN-2-YL)ETHYL)-1,2,3,4-TETRAHYDRONAPHTHALEN-2-AMINE

DownStream

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%