Refametinib (R enantiomer)

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Names

[ CAS No. ]:
923032-38-6

[ Name ]:
Refametinib (R enantiomer)

[Synonym ]:
Cyclopropanesulfonamide, N-[3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]-6-methoxyphenyl]-1-(2,3-dihydroxypropyl)-
Refametinib (R enantiomer)
N-{3,4-Difluoro-2-[(2-fluoro-4-iodophenyl)amino]-6-methoxyphenyl}-1-(2,3-dihydroxypropyl)cyclopropanesulfonamide
Refametinib
Refametinib R enantiomer

Chemical & Physical Properties

[ Density]:
1.8±0.1 g/cm3

[ Boiling Point ]:
566.9±60.0 °C at 760 mmHg

[ Molecular Formula ]:
C19H20F3IN2O5S

[ Molecular Weight ]:
572.337

[ Flash Point ]:
296.7±32.9 °C

[ Exact Mass ]:
572.008972

[ PSA ]:
116.27000

[ LogP ]:
4.78

[ Vapour Pressure ]:
0.0±1.6 mmHg at 25°C

[ Index of Refraction ]:
1.660

Related Compounds

  • Talarozole (R enantiomer)
  • Tenalisib R Enantiomer
  • GLPG0492 (R enantiomer)
  • RSV604 R enantiomer
  • Bitopertin (R enantiomer)
  • Cobimetinib (R-enantiomer)
  • N-(2,4-dimethoxyphenyl)-2-[(6-phenyl[1,2,4]triazolo[3,4-a]phthalazin-3-yl)sulfanyl]acetamide
  • 2-(2-(((3,5-Dimethyl-1-phenyl-1H-pyrazol-4-yl)methyl)(methyl)amino)propanamido)-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxamide
  • 4-chloro-3,5-bis(3,4-dimethoxyphenyl)-1-[3-(trifluoromethyl)benzyl]-1H-pyrazole
  • N-(2,5-dimethoxyphenyl)-2-[(6-phenyl[1,2,4]triazolo[3,4-a]phthalazin-3-yl)sulfanyl]acetamide
  • N-(3,4-dimethoxyphenyl)-2-[(6-phenyl[1,2,4]triazolo[3,4-a]phthalazin-3-yl)sulfanyl]acetamide
  • 4-(N-benzyl-N-methylsulfamoyl)-N-(5-(2-(methylthio)phenyl)-1,3,4-oxadiazol-2-yl)benzamide
  • 2-[3,5-Bis[4-(difluoromethoxy)phenyl]-1H-pyrazol-1-yl]-4-(1,3-dimethyl-1H-pyrazol-4-yl)-6-(trifluoromethyl)pyrimidine
  • 4-(N,N-dimethylsulfamoyl)-N-(5-(2-(methylsulfonyl)phenyl)-1,3,4-oxadiazol-2-yl)benzamide
  • 2-[3,5-bis(3-methoxyphenyl)-4-methyl-1H-pyrazol-1-yl]-4-(furan-2-yl)-6-(trifluoromethyl)pyrimidine
  • 2-[3,5-Bis(3,4-dimethoxyphenyl)-4-methyl-1H-pyrazol-1-yl]-4-(2-thienyl)-6-(trifluoromethyl)pyrimidine
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