Nilotinib monohydrochloride monohydrate

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Names

[ CAS No. ]:
923288-90-8

[ Name ]:
Nilotinib monohydrochloride monohydrate

[Synonym ]:
Nilotinib hydrochloride monohydrate
4-Methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-{[4-(3-pyridinyl)-2-pyrimidinyl]amino}benzamide hydrochloride hydrate
Tasigna (TN)
Benzamide, 4-methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]-, hydrochloride, hydrate (1:1:1)
4-methyl-N-[3-(4-methyl-imidazol-1-yl)-5-trifluoromethyl-phenyl]-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-benzamide monohydrochloride monohydrate
Nilotinib hydrochloride hydrate
5JHU0N1R6K
Nilotinib (monohydrochloride monohydrate)
Nilotinib hydrochloride hydrate (JAN)
UNII-5JHU0N1R6K
Nilotinib monohydrochloride monohydrate

Chemical & Physical Properties

[ Molecular Formula ]:
C28H25ClF3N7O2

[ Molecular Weight ]:
583.992

[ Exact Mass ]:
583.171021

[ PSA ]:
101.11000

[ LogP ]:
6.81280

Synthetic Route

Precursor & DownStream

Precursor

  • Nilotinib (AMN-107)

DownStream


Related Compounds

  • l-histidine monohydrochloride monohydrate
  • 1-(2-Chlorophenyl)piperazine Monohydrochloride Monohydrate
  • (2S)-2,7-diamino-7-iminoheptanoic acid,hydrochloride
  • Tirofiban hydrochloride
  • Doxapram (hydrochloride hydrate)
  • Bepridil hydrochloride
  • 3a(2)-Thymidylic acid, 2a(2)-deoxyguanylyl-(3a(2)a5a(2))-2a(2)-deoxyadenylyl-(3a(2)a5a(2))-2a(2)-deoxycytidylyl-(3a(2)a5a(2))-thymidylyl-(3a(2)a5a(2))-2a(2)-deoxyguanylyl-(3a(2)a5a(2))-2a(2)-deoxyadenylyl-(3a(2)a5a(2))-2a(2)-deoxycytidylyl-(3a(2)a5a(2))-, 3a(2)-[2-[2-(2-hydroxyethoxy)ethoxy]ethyl] ester
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 1-(3,3,4,4,5,5,6,6,7,7,8,8,8-Tridecafluorooctylsulfinyl)-3-(trimethylazaniumyl)propan-2-olate
  • 2-(2,5-Dichlorophenyl)-3-methoxy-6-(trifluoromethyl)pyridine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • N-((1r,4r)-4-((3-cyanopyrazin-2-yl)oxy)cyclohexyl)benzofuran-2-carboxamide
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • N-((6-(2-methoxyethoxy)pyridin-3-yl)methyl)-4,5,6,7-tetrahydro-1H-benzo[d]imidazole-5-carboxamide
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol