RAF265 (CHIR-265)

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Names

[ CAS No. ]:
927880-90-8

[ Name ]:
RAF265 (CHIR-265)

[Synonym ]:
,CHIR-265,,CHIR265
RAF265(CHIR-265)
{1-Methyl-5-[2-(5-trifluoromethyl-1H-imidazol-2-yl)-pyridin-4-yloxy]-1H-benzoimidazol-2-yl}-(4-trifluoromethylphenyl)-amine
1-Methyl-5-[[2-[5-(trifluoromethyl)-1h-imidazol-2-yl]-4-pyridinyl]oxy]-n-[4-(trifluoromethyl)phenyl]-1h-benzimidazol-2-amine
{1-methyl-5-[2-(5-trifluoromethyl-1H-imidazol-2-yl)-pyridin-4-yIoxy]-1H-benzoimidazol-2-yl}-(4-trifluoromethyl-phenyl)amine
1H-Benzimidazol-2-amine, 1-methyl-5-[[2-[5-(trifluoromethyl)-1H-imidazol-2-yl]-4-pyridinyl]oxy]-N-[4-(trifluoromethyl)phenyl]-
CHIR265
1-Methyl-5-({2-[4-(trifluoromethyl)-1H-imidazol-2-yl]-4-pyridinyl}oxy)-N-[4-(trifluoromethyl)phenyl]-1H-benzimidazol-2-amine
RAF265
1-methyl-5-(2-(5-(trifluoromethyl)-1H-imidazol-2-yl)pyridin-4-yloxy)-N-(4-(trifluoromethyl)phenyl)-1H-benzo[d]imidazol-2-amine

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
667.6±65.0 °C at 760 mmHg

[ Molecular Formula ]:
C24H16F6N6O

[ Molecular Weight ]:
518.414

[ Flash Point ]:
357.5±34.3 °C

[ Exact Mass ]:
518.128967

[ PSA ]:
80.65000

[ LogP ]:
6.03

[ Vapour Pressure ]:
0.0±2.0 mmHg at 25°C

[ Index of Refraction ]:
1.622

[ Storage condition ]:
-20℃

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 1,2-Benzenediamine, N1-methyl-4-[[2-[5-(trifluoromethyl)-1H-imidazol-2-yl]-4-pyridinyl]oxy]
  • p-Trifluoromethylphenylisothiocyanate
  • 1-Bromo-3,3,3-trifluoroacetone

DownStream

Related Compounds

  • Raf265 derivative
  • nicocortonide
  • compound 78-265
  • Kerosene
  • Cuprate(2-), [29H,31H-phthalocyaninedisulfonato(4-)-N29,N30,N31,N32]-, dihydrogen, compds. with N,N'-bis(Ph and o-tolyl and xylyl)guanidine (1:2)
  • Ethanol, 2-(methylamino)-, N-C12-18-alkyl derivs., hydrogen sulfates (esters), N-oxides, sodium salts
  • 3-(2-(2,5-Dioxopyrrolidin-1-yl)acetamido)cyclohexyl (4-fluorophenyl)carbamate
  • N-(4-(1H-tetrazol-1-yl)phenyl)-6-oxo-2,3,4,6-tetrahydropyrimido[2,1-b][1,3]thiazine-3-carboxamide
  • 3-(5-Methylthiophene-2-sulfonamido)cyclohexyl (4-fluorophenyl)carbamate
  • tert-Butyl 8-ethyl-2,8-diazaspiro[4.5]decane-2-carboxylate
  • N-((1-ethylpyrrolidin-2-yl)methyl)-1,1,1-trifluoromethanamine
  • N-((1-ethylpiperidin-2-yl)methyl)-1,1,1-trifluoromethanamine
  • N-ethyl-1-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)ethanamine
  • N-ethyl-1-(1-isopropyl-1H-imidazol-2-yl)ethanamine
  • tert-Butyl 3-(1-(ethylamino)ethyl)azetidine-1-carboxylate
  • 2-((Cyclopropylmethyl)amino)-4-phenylpyrimidine-5-carboxylic acid
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