RAF265 (CHIR-265)

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Names

[ CAS No. ]:
927880-90-8

[ Name ]:
RAF265 (CHIR-265)

[Synonym ]:
,CHIR-265,,CHIR265
RAF265(CHIR-265)
{1-Methyl-5-[2-(5-trifluoromethyl-1H-imidazol-2-yl)-pyridin-4-yloxy]-1H-benzoimidazol-2-yl}-(4-trifluoromethylphenyl)-amine
1-Methyl-5-[[2-[5-(trifluoromethyl)-1h-imidazol-2-yl]-4-pyridinyl]oxy]-n-[4-(trifluoromethyl)phenyl]-1h-benzimidazol-2-amine
{1-methyl-5-[2-(5-trifluoromethyl-1H-imidazol-2-yl)-pyridin-4-yIoxy]-1H-benzoimidazol-2-yl}-(4-trifluoromethyl-phenyl)amine
1H-Benzimidazol-2-amine, 1-methyl-5-[[2-[5-(trifluoromethyl)-1H-imidazol-2-yl]-4-pyridinyl]oxy]-N-[4-(trifluoromethyl)phenyl]-
CHIR265
1-Methyl-5-({2-[4-(trifluoromethyl)-1H-imidazol-2-yl]-4-pyridinyl}oxy)-N-[4-(trifluoromethyl)phenyl]-1H-benzimidazol-2-amine
RAF265
1-methyl-5-(2-(5-(trifluoromethyl)-1H-imidazol-2-yl)pyridin-4-yloxy)-N-(4-(trifluoromethyl)phenyl)-1H-benzo[d]imidazol-2-amine

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
667.6±65.0 °C at 760 mmHg

[ Molecular Formula ]:
C24H16F6N6O

[ Molecular Weight ]:
518.414

[ Flash Point ]:
357.5±34.3 °C

[ Exact Mass ]:
518.128967

[ PSA ]:
80.65000

[ LogP ]:
6.03

[ Vapour Pressure ]:
0.0±2.0 mmHg at 25°C

[ Index of Refraction ]:
1.622

[ Storage condition ]:
-20℃

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 1,2-Benzenediamine, N1-methyl-4-[[2-[5-(trifluoromethyl)-1H-imidazol-2-yl]-4-pyridinyl]oxy]
  • p-Trifluoromethylphenylisothiocyanate
  • 1-Bromo-3,3,3-trifluoroacetone

DownStream

Related Compounds

  • Raf265 derivative
  • nicocortonide
  • compound 78-265
  • Kerosene
  • Cuprate(2-), [29H,31H-phthalocyaninedisulfonato(4-)-N29,N30,N31,N32]-, dihydrogen, compds. with N,N'-bis(Ph and o-tolyl and xylyl)guanidine (1:2)
  • Ethanol, 2-(methylamino)-, N-C12-18-alkyl derivs., hydrogen sulfates (esters), N-oxides, sodium salts
  • Ammonium perfluoro-2-{[1-(1,2-dichloro-1,2,2-trifluoroethoxy)propan-2-yl]oxy}ethane-1-sulfonate
  • 3-[[(Perfluorohexyl)sulfonyl]amino]-N,N,N-trimethyl-1-propanaminium chloride, sodium salt (1:1:1)
  • N-[2-[[2-[(2-Aminoethyl)amino]ethyl]amino]ethyl]-N-ethyl-perfluoro-1-octanesulfonamide
  • 2-(Acetyloxy)-N-(carboxymethyl)-N,N-dimethyl-3-(perfluorohexadecyl)-1-propanaminium
  • 30,30,31,31,31-Pentafluoro-29-(1,1,2,2,2-pentafluoroethyl)-27,28,29-tris(trifluoromethyl)-2,5,8,11,14,17,20,23,26-nonaoxahentriacont-27-ene
  • Tetrabutylphosphonium perfluorohexane sulfonate
  • N-[3-(Trimethoxysilyl)propyl]perfluoroundecanamide
  • N,N,N-Trimethyl-3-[(perfluoro-1-oxoheptyl)amino]-1-propanaminium iodide
  • 2-Hydroxy-3-[(perfluoroheptyl)methoxy]propyl heneicosanoate
  • 1-((Perfluoro-6-(1-methylethoxy)hexyl)ethyl)pyridinium sulfate (2:1)
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