Osilodrostat

Suppliers

Names

[ Name ]:
Osilodrostat

[Synonym ]:
osilodrostat
4-(quinolin-3-ylmethyl-amino)-benzenesulfonamide
Novartis LCI699
(R)-4-(6,7-dihydro-5H-pyrrolo[1,2-c]imidazol-5-yl)-3-fluorobenzonitrile
UNII-5YL4IQ1078
4-[(5R)-6,7-Dihydro-5H-pyrrolo[1,2-c]imidazol-5-yl]-3-fluorobenzonitrile
Benzonitrile, 4-[(5R)-6,7-dihydro-5H-pyrrolo[1,2-c]imidazol-5-yl]-3-fluoro-
3-<N-(4'-Amidosulfonylphenyl)aminomethyl>quinoline
4-((R)-6,7-dihydro-5H-pyrrolo[1,2-c]imidazol-5-yl)-3-fluoro-benzonitrile

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
433.8±45.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₃H₁₀FN₃

[ Molecular Weight ]:
227.237

[ Flash Point ]:
216.2±28.7 °C

[ Exact Mass ]:
227.085876

[ PSA ]:
41.61000

[ LogP ]:
1.13

[ Vapour Pressure ]:
0.0±1.0 mmHg at 25°C

[ Index of Refraction ]:
1.664

[ Storage condition ]:
-20℃

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

2-Fluoro-4-Cyanobenzyl Bromide
3-Fluoro-4-methylbenzonitrile
2-(1-tritylimidazol-4-yl)acetic acid
1H-Imidazole, 4-[2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]ethyl]-1-(triphenylmethyl)
4-((5-(2-((tert-butyldimethylsilanyl)oxy)ethyl)-1H-imidazol-1-yl)methyl)-3-fluorobenzonitrile