3',4'-DICHLOROBENZAMIL HYDROCHLORIDE

Names

[ CAS No. ]:
928621-15-2

[ Name ]:
3',4'-DICHLOROBENZAMIL HYDROCHLORIDE

Chemical & Physical Properties

[ Molecular Formula ]:
C13H13Cl4N7O

[ Molecular Weight ]:
425.1

[ Appearance of Characters ]:
solid

[ Storage condition ]:
2-8°C

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
22

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Articles

Amiloride derivatives are potent blockers of KATP channels.

Naunyn Schmiedebergs Arch. Pharmacol. 364(4) , 351-8, (2001)

In cardiomyocytes sarcolemmal KATP channels open massively when the cytosolic [ATP] drops into the range of tens of micromolar, as during acute ischemia. The diuretic drug amiloride and related deriva...

Modulation of neuroprotective effect of ischemic post-conditioning by dichlorobenzamil a Na(+)/Ca(2+) exchanger inhibitor in mice.

Biol. Pharm. Bull. 33(4) , 585-91, (2010)

The present study has been designed to investigate the modulatory role of dichlorobenzamil a Na(+)/Ca(2+) exchanger inhibitor in ischemic post-conditioning-induced neuroprotection in mice. Bilateral c...

Stimulation of large-conductance Ca2+-activated K+ channels by the Na+/Ca2+ exchanger inhibitor dichlorobenzamil in cultured human umbilical vein endothelial cells and mouse aortic smooth muscle cells.

J. Physiol. Pharmacol. 60(1) , 43-50, (2009)

We investigated the effects of the selective inhibitor of Na(+)/Ca(2+) exchanger (NCX), 2',4'- and 3',4'-dichlorobenzamil (DCB), on large-conductance Ca(2+)-activated K(+) (BK(Ca)) channels in culture...


More Articles

Related Compounds

  • 3' 4'-DICHLOROBENZAMIL
  • 2',4'-dichlorobenzamil hydrochloride
  • 3',4'-Methylenedioxy-α-pyrrolidinopropiophenone Hydrochloride
  • 3'-4'-dichloro-6-methoxyhexanophenone O(-2-aminoethyl) oxime hydrochloride
  • 3',4'-DIMETHYLBIPHENYL-2-YLAMINEHYDROCHLORIDE
  • 3',4'-dihydrospiro[azetidine-3,2'-[1]benzopyran]-4'-one hydrochloride
  • 2-(Methoxymethyl)-5-(2-methyloxiran-2-yl)furan
  • methyl (3S)-3-(4-{[(tert-butoxy)carbonyl]amino}-3-methylphenyl)-3-hydroxypropanoate
  • 1-[2-(Dimethylamino)pyridin-3-yl]cyclopropane-1-carboxylic acid
  • N-[4-(2-amino-3-hydroxy-2-methylpropyl)phenyl]acetamide
  • 4-[2-(Methoxymethyl)-1,3-thiazol-4-yl]-2-methylbutan-2-amine
  • 4-(5-Chloropyridin-2-yl)-2-methylbutanoic acid
  • 4-[(1-ethyl-1H-imidazol-5-yl)methyl]-4-methoxypiperidine
  • 5-(3-methoxy-4-nitrophenyl)-1H-imidazol-2-amine
  • 4-(4-Bromo-3-methoxyphenyl)-1,3-oxazolidin-2-one
  • 4-methyl-6-[(2R)-oxiran-2-yl]-3,4-dihydro-2H-1,4-benzoxazine
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