3',4'-DICHLOROBENZAMIL HYDROCHLORIDE

Names

[ CAS No. ]:
928621-15-2

[ Name ]:
3',4'-DICHLOROBENZAMIL HYDROCHLORIDE

Chemical & Physical Properties

[ Molecular Formula ]:
C13H13Cl4N7O

[ Molecular Weight ]:
425.1

[ Appearance of Characters ]:
solid

[ Storage condition ]:
2-8°C

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
22

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Articles

Amiloride derivatives are potent blockers of KATP channels.

Naunyn Schmiedebergs Arch. Pharmacol. 364(4) , 351-8, (2001)

In cardiomyocytes sarcolemmal KATP channels open massively when the cytosolic [ATP] drops into the range of tens of micromolar, as during acute ischemia. The diuretic drug amiloride and related deriva...

Modulation of neuroprotective effect of ischemic post-conditioning by dichlorobenzamil a Na(+)/Ca(2+) exchanger inhibitor in mice.

Biol. Pharm. Bull. 33(4) , 585-91, (2010)

The present study has been designed to investigate the modulatory role of dichlorobenzamil a Na(+)/Ca(2+) exchanger inhibitor in ischemic post-conditioning-induced neuroprotection in mice. Bilateral c...

Stimulation of large-conductance Ca2+-activated K+ channels by the Na+/Ca2+ exchanger inhibitor dichlorobenzamil in cultured human umbilical vein endothelial cells and mouse aortic smooth muscle cells.

J. Physiol. Pharmacol. 60(1) , 43-50, (2009)

We investigated the effects of the selective inhibitor of Na(+)/Ca(2+) exchanger (NCX), 2',4'- and 3',4'-dichlorobenzamil (DCB), on large-conductance Ca(2+)-activated K(+) (BK(Ca)) channels in culture...


More Articles

Related Compounds

  • 3' 4'-DICHLOROBENZAMIL
  • 2',4'-dichlorobenzamil hydrochloride
  • 3',4'-Methylenedioxy-α-pyrrolidinopropiophenone Hydrochloride
  • 3'-4'-dichloro-6-methoxyhexanophenone O(-2-aminoethyl) oxime hydrochloride
  • 3',4'-DIMETHYLBIPHENYL-2-YLAMINEHYDROCHLORIDE
  • 3',4'-dihydrospiro[azetidine-3,2'-[1]benzopyran]-4'-one hydrochloride
  • 5-Ethyl-6-methyl-2-(phenylmethoxy)-3-pyridinecarboxaldehyde
  • 2-[(4-chlorophenyl)(hydroxy)methylene]malonaldehyde bis[O-(2,4-dichlorobenzyl)oxime]
  • 10,10-Dimethyl-4-azatricyclo[5.2.1.0,1,5]decane
  • 2-(Benzylamino)-3-methylbutan-1-ol
  • N'-[2-(4-chlorophenoxy)ethanimidoyl]-3-{[3-(trifluoromethyl)benzyl]oxy}-2-thiophenecarbohydrazide
  • [5-(4-Chlorophenyl)-3-oxo-4-pentenylidene](methyl)ammoniumolate
  • Imidazo[1,2-a]pyridine,3-[[4-(2-chlorophenyl)-1-piperazinyl]methyl]-
  • Ethyl 4-((5-(3-(methylthio)phenyl)-1,2,4-oxadiazol-3-yl)methyl)piperazine-1-carboxylate
  • 1-(2-{[3-chloro-5-(trifluoromethyl)-2-pyridinyl]amino}ethyl)-5-[1-(dimethylamino)ethylidene]-2,4,6(1H,3H,5H)-pyrimidinetrione
  • N-(4-chlorophenyl)-N'-(2-methyl-2-{[3-(trifluoromethyl)benzyl]sulfanyl}propyl)urea
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