3',4'-DICHLOROBENZAMIL HYDROCHLORIDE

Names

[ CAS No. ]:
928621-15-2

[ Name ]:
3',4'-DICHLOROBENZAMIL HYDROCHLORIDE

Chemical & Physical Properties

[ Molecular Formula ]:
C13H13Cl4N7O

[ Molecular Weight ]:
425.1

[ Appearance of Characters ]:
solid

[ Storage condition ]:
2-8°C

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
22

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Articles

Amiloride derivatives are potent blockers of KATP channels.

Naunyn Schmiedebergs Arch. Pharmacol. 364(4) , 351-8, (2001)

In cardiomyocytes sarcolemmal KATP channels open massively when the cytosolic [ATP] drops into the range of tens of micromolar, as during acute ischemia. The diuretic drug amiloride and related deriva...

Modulation of neuroprotective effect of ischemic post-conditioning by dichlorobenzamil a Na(+)/Ca(2+) exchanger inhibitor in mice.

Biol. Pharm. Bull. 33(4) , 585-91, (2010)

The present study has been designed to investigate the modulatory role of dichlorobenzamil a Na(+)/Ca(2+) exchanger inhibitor in ischemic post-conditioning-induced neuroprotection in mice. Bilateral c...

Stimulation of large-conductance Ca2+-activated K+ channels by the Na+/Ca2+ exchanger inhibitor dichlorobenzamil in cultured human umbilical vein endothelial cells and mouse aortic smooth muscle cells.

J. Physiol. Pharmacol. 60(1) , 43-50, (2009)

We investigated the effects of the selective inhibitor of Na(+)/Ca(2+) exchanger (NCX), 2',4'- and 3',4'-dichlorobenzamil (DCB), on large-conductance Ca(2+)-activated K(+) (BK(Ca)) channels in culture...


More Articles

Related Compounds

  • 3' 4'-DICHLOROBENZAMIL
  • 2',4'-dichlorobenzamil hydrochloride
  • 3',4'-Methylenedioxy-α-pyrrolidinopropiophenone Hydrochloride
  • 3'-4'-dichloro-6-methoxyhexanophenone O(-2-aminoethyl) oxime hydrochloride
  • 3',4'-DIMETHYLBIPHENYL-2-YLAMINEHYDROCHLORIDE
  • 3',4'-dihydrospiro[azetidine-3,2'-[1]benzopyran]-4'-one hydrochloride
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 2-methyl-N'-(5-methylthiophene-2-carbonyl)furan-3-carbohydrazide
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine
  • 6-[3-(2-Cyclopropyl-pyrimidin-4-yl)-1H-pyrazol-4-yl]-quinoxaline