(6R,12aS)-6-benzo[1,3]dioxol-5-yl-2,3,6,7,12,12a-hexahydropyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione

Names

[ CAS No. ]:
929100-66-3

[ Name ]:
(6R,12aS)-6-benzo[1,3]dioxol-5-yl-2,3,6,7,12,12a-hexahydropyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione

[Synonym ]:
N-Desmethyl ent-Tadalafil

Chemical & Physical Properties

[ Molecular Formula ]:
C21H17N3O4

[ Molecular Weight ]:
375.37700

[ Exact Mass ]:
375.12200

[ PSA ]:
83.66000

[ LogP ]:
2.13580

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • (1R,3S)-1-benzo[1,3]dioxol-5-yl-2-(2-chloroacetyl)-2,3,4,9-tetrahydro-1H-β-carboline-3-carboxylic acid methyl ester

DownStream

Related Compounds

  • 2-{2-[4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)oxan-4-yl]acetamido}-2-methylbutanoic acid
  • 2-[(2S,3S)-N-benzyl-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-methylpentanamido]acetic acid
  • 2-[N-benzyl-2-ethyl-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanamido]acetic acid
  • 2-{N-benzyl-2-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]pentanamido}acetic acid
  • 2-{N-benzyl-2-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]-3-methylbutanamido}acetic acid
  • 2-[N-benzyl-4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-4-methylpentanamido]acetic acid
  • 2-[N-benzyl-4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-methoxybutanamido]acetic acid
  • 2-{N-benzyl-3-[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)ethoxy]propanamido}acetic acid
  • 2-{N-benzyl-1-[4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)phenyl]formamido}acetic acid
  • 2-{N-benzyl-2-[4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)phenyl]-2-methylpropanamido}acetic acid