2-Naphthoic acid

Names

[ CAS No. ]:
93-09-4

[ Name ]:
2-Naphthoic acid

[Synonym ]:
2-Naphthoic acid
isonaphthoic acid
β-Naphthoic acid
2-Naphthalenecarboxylic acid
naphthalene-2-carboxylic acid
EINECS 202-217-8
MFCD00004101
2-napthoic acid

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
332.9±11.0 °C at 760 mmHg

[ Melting Point ]:
185-187 °C(lit.)

[ Molecular Formula ]:
C₁₁H₈O₂

[ Molecular Weight ]:
172.180

[ Flash Point ]:
151.3±13.9 °C

[ Exact Mass ]:
172.052429

[ PSA ]:
37.30000

[ LogP ]:
3.13

[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C

[ Index of Refraction ]:
1.673

[ Water Solubility ]:
<0.5 g/L (20 C)

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: QL1050000

CHEMICAL NAME :: 2-Naphthoic acid

CAS REGISTRY NUMBER :: 93-09-4

BEILSTEIN REFERENCE NO. :: 0972039

LAST UPDATED :: 199712

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C11-H8-O2

MOLECULAR WEIGHT :: 172.19

WISWESSER LINE NOTATION :: L66J CVQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 4500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982 Volume(issue)/page/year: -,90,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 4700 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982 Volume(issue)/page/year: -,90,1982

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 500 mg/kg

TOXIC EFFECTS :: Behavioral - altered sleep time (including change in righting reflex) Lungs, Thorax, or Respiration - other changes

REFERENCE :: CBCCT* "Summary Tables of Biological Tests," National Research Council Chemical-Biological Coordination Center. (National Academy of Science Library, 2101 Constitution Ave., NW, Washington, DC 20418) Volume(issue)/page/year: 4,379,1952 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-RUSSIA:STEL 0.1 mg/m3 JAN 1993

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
2

[ RTECS ]:
QL1050000

[ HS Code ]:
2916399090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

2-Naphthalenemethanol
(1S)-1-naphthalen-2-ylethane-1,2-diol
2-Methylnaphthalene
Carbon dioxide
5,5-Dimethyl-2-(naphthalen-2-yl)-1,3,2-dioxaborinane
2-Bromonaphthalene
carbon monoxide
2-IODONAPHTHALENE
1,3-Butanedione,1-(2-naphthalenyl)-

DownStream

2-NAPHTHHYDRAZIDE
2-Bromonaphthalene
2-naphthalen-2-yl-1,3-benzoxazole
METHYL3-METHOXYTHIOPHENE-2-CARBOXYLATE
2-(brommethyl)naphthalen
3-Hydroxy-2-naphthoic acid
N-PHENYL-2,3-NAPHTHALIMIDE
2-phenyl-1H-benzo[e]isoindole-1,3(2H)-dione
3-Bromo-2-naphthoic acid

Customs

[ HS Code ]: 2916399090

[ Summary ]:
2916399090 other aromatic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

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