Naphthalene-2-sulfonyl chloride

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Names

[ CAS No. ]:
93-11-8

[ Name ]:
Naphthalene-2-sulfonyl chloride

[Synonym ]:
EINECS 202-219-9
MFCD00004087
β-Naphthalenesulfonyl chloride
2-naphthylsulfonyl chloride
naphthalene-2-sulfonyl chloride
Naphthalene-2-sulfonic acid chloride
2-Naphthalenesulfonyl chloride

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
371.3±11.0 °C at 760 mmHg

[ Melting Point ]:
74-76 °C(lit.)

[ Molecular Formula ]:
C10H7ClO2S

[ Molecular Weight ]:
226.679

[ Flash Point ]:
178.4±19.3 °C

[ Exact Mass ]:
225.985519

[ PSA ]:
42.52000

[ LogP ]:
3.22

[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C

[ Index of Refraction ]:
1.643

[ Water Solubility ]:
insoluble

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS05

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H314

[ Precautionary Statements ]:
P280-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ Hazard Codes ]:
C:Corrosive;

[ Risk Phrases ]:
R34

[ Safety Phrases ]:
S26-S36/37/39-S45

[ RIDADR ]:
UN 3261 8/PG 2

[ WGK Germany ]:
3

[ Packaging Group ]:
II

[ Hazard Class ]:
8

[ HS Code ]:
29049020

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 2-Naphthalenethiol
  • Disulfide,1,2-di-2-naphthalenyl
  • Sodium 1-naphthalenesulfonate
  • 2-Naphthalenesulfonic acid
  • 2-benzylsulfanylnaphthalene
  • Naphthalene
  • 2-Naphthaleneboronic acid
  • Benzotrichloride
  • 2-Bromonaphthalene

DownStream

  • 5-ethoxy-1-naphthalen-2-ylsulfonylpyrrolidin-2-one
  • 2-IODONAPHTHALENE
  • 2-naphthalen-2-yl-1,3-benzoxazole
  • Dithiodiglycolic acid
  • naphthalene-2-sulfinic acid
  • 2-Naphthalenethiol
  • Disulfide,1,2-di-2-naphthalenyl
  • 2-Methylnaphthalene
  • Naphthalene, 2-phenyl-
  • 2-Vinylnaphthalene

Customs

[ HS Code ]: 2904909090

[ Summary ]:
HS:2904909090 sulphonated, nitrated or nitrosated derivatives of hydrocarbons, whether or not halogenated VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

Articles

Derivatization of primary amines by 2-naphthalenesulfonyl chloride for high-performance liquid chromatographic assay of neomycin sulfate.

J. Chromatogr. A. 369(1) , 105-15, (1986)

A normal phase high-performance liquid chromatographic (HPLC) method has been developed for the assay of neomycin sulfate. The method involves pre-column derivatization with 2-naphthalenesulfonyl chlo...

From histamine to imidazolylalkyl-sulfonamides: the design of a novel series of histamine H3-receptor antagonists.

Bioorg. Med. Chem. Lett. 9(13) , 1825-30, (1999)

Histamine was converted to a selective histamine H3-receptor antagonist by capping the primary amine with 2-naphthalenesulfonyl chloride. Higher receptor affinity and lower variability in the data fro...

Derivatization of secondary amines with 2-naphthalene-sulfonyl chloride for high-performance liquid chromatographic analysis of spectinomycin.

J. Chromatogr. A. 333(2) , 365-80, (1985)

A normal-phase high-performance liquid chromatographic (HPLC) method has been developed for the assay of spectinomycin hydrochloride and spectinomycin sulfate for detection at 254 nm. The method invol...


More Articles

Related Compounds

  • 1-butylnaphthalene-2-sulfonyl chloride
  • 7-chlornaphthalene-2-sulfonyl chloride
  • 6-ethoxynaphthalene-2-sulfonyl chloride
  • 6-bromo-naphthalene-2-sulfonyl chloride
  • 6-Chloronaphthalene-2-sulfonyl chloride
  • 8-nitro-naphthalene-2-sulfonyl chloride
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 6-[4-(Dimethylamino)butoxy]pyridine-2-carboxylic acid
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • 2-(4-Chloro-2-fluorophenyl)-2-methylpropanoic acid
  • 1-(2-fluoroethyl)-4-iodopyridin-2(1H)-one
  • N-(1,2,4-thiadiazol-5-yl)acetamide
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide