Acetylisoeugenol

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Names

[ CAS No. ]:
93-29-8

[ Name ]:
Acetylisoeugenol

[Synonym ]:
2-Methoxy-4-[(1E)-1-propenyl]phenyl acetate
EINECS 202-236-1
2-Methoxy-4-[(1E)-prop-1-en-1-yl]phenyl acetate
Phenol, 2-methoxy-4-[(1E)-1-propen-1-yl]-, acetate
MFCD00026984
2-Methoxy-4-[(1E)-1-propen-1-yl]phenylacetat
2-Methoxy-4-[(1E)-1-propen-1-yl]phenyl acetate
Phenol, 2-methoxy-4-(1-propenyl)-, acetate, (E)-
Acétate de 2-méthoxy-4-[(1E)-1-propèn-1-yl]phényle
1-acetoxy-2-methoxy-4-(1-propenyl)benzene

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
283.0±20.0 °C at 760 mmHg

[ Melting Point ]:
79-81 °C(lit.)

[ Molecular Formula ]:
C12H14O3

[ Molecular Weight ]:
206.238

[ Flash Point ]:
113.9±16.4 °C

[ Exact Mass ]:
206.094299

[ PSA ]:
35.53000

[ LogP ]:
2.54

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.539

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
SL7940000
CHEMICAL NAME :
Phenol, 2-methoxy-4-propenyl-, acetate
CAS REGISTRY NUMBER :
93-29-8
LAST UPDATED :
199712
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C12-H14-O3
MOLECULAR WEIGHT :
206.26
WISWESSER LINE NOTATION :
2U1R CO1 DOV1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
3450 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 13,819,1975
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
>5 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 13,819,1975 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83234 No. of Facilities: 21 (estimated) No. of Industries: 1 No. of Occupations: 2 No. of Employees: 394 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83234 No. of Facilities: 7 (estimated) No. of Industries: 1 No. of Occupations: 5 No. of Employees: 1557 (estimated) No. of Female Employees: 276 (estimated)

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
2

[ RTECS ]:
SL7940000

Articles

Parallel dual secondary column-dual detection: a further way of enhancing the informative potential of two-dimensional comprehensive gas chromatography.

J. Chromatogr. A. 1360 , 264-74, (2014)

Comprehensive two-dimensional gas chromatography (GC×GC) coupled with Mass Spectrometry (MS) is one of today's most powerful analytical platforms for detailed analysis of medium-to-high complexity sam...

Isoeugenol is an important contact allergen: can it be safely replaced with isoeugenyl acetate?

Contact Dermatitis 41(5) , 272-5, (1999)

The prevalence of contact allergy to the fragrance mix in individuals with eczema is up to 10%. Within the mix, isoeugenol (CAS 97-54-1) is an important individual allergen. Until May 1998, the IFRA (...

Contact allergy to isoeugenol and its derivatives: problems with allergen substitution.

Contact Dermatitis 51(5-6) , 288-91, (2004)

A total of 2261 (808 male, 1453 female) consecutive patients attending contact dermatitis clinics were patch tested to isoeugenol and its derivatives listed in the EU Inventory of Fragrance Ingredient...


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