5-Aminouracil

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Names

[ CAS No. ]:
932-52-5

[ Name ]:
5-Aminouracil

[Synonym ]:
2,4(1H,3H)-Pyrimidinedione, 5-amino-
4-Amino-2,6-dihydroxypyrimidine
6-Amino-2,4(1H,3H)-pyrimidinedione
2,4(1H,3H)-Pyrimidinedione, 6-amino-
2,4-Dihydroxy-5-aminopyrimidine
5-Amino-2,4-dihydroxypyrimidine
URACIL,5-AMINO
5-aminopyrimidine-2,4(1H,3H)-dione
6-aminopyrimidine-2,4-diol
Pyrimidine, 2,4-dihydroxy-6-amino
5-aminouracyl
MFCD00006025
2,4-Dihydroxy-6-aminopyrimidine
6-aminopyrimidine-2,4(1H,3H)-dione
5-Amino-2,4-pyrimidinediol
EINECS 213-252-3
5-Aminouracil
6-Aminouracil
5-Amino-2,4(1H,3H)-pyrimidinedione
5-Amino-1H-pyrimidin-2,4-dion

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
580.4±53.0 °C at 760 mmHg

[ Melting Point ]:
>300 °C(lit.)

[ Molecular Formula ]:
C4H5N3O2

[ Molecular Weight ]:
127.101

[ Flash Point ]:
304.8±30.9 °C

[ Exact Mass ]:
127.038177

[ PSA ]:
91.74000

[ LogP ]:
-1.38

[ Vapour Pressure ]:
0.0±1.7 mmHg at 25°C

[ Index of Refraction ]:
1.545

[ Water Solubility ]:
0.5 g/L (20 ºC)

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
YQ8740000
CHEMICAL NAME :
Uracil, 5-amino-
CAS REGISTRY NUMBER :
932-52-5
LAST UPDATED :
199701
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C4-H5-N3-O2
MOLECULAR WEIGHT :
127.12
WISWESSER LINE NOTATION :
T6MVMVJ EZ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :
DNA inhibition
TEST SYSTEM :
Human HeLa cell
DOSE/DURATION :
5 mmol/L
REFERENCE :
RAREAE Radiation Research. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1954- Volume(issue)/page/year: 37,334,1969

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
R22

[ Safety Phrases ]:
S22-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
YQ8740000

[ HS Code ]:
2933599090

Synthetic Route

Customs

[ HS Code ]: 2933599090

[ Summary ]:
2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Effect of amino substitution on the excited state dynamics of uracil.

Photochem. Photobiol. Sci. 7(7) , 765-8, (2008)

The excited state deactivation of two amino-substituted uracils, 5-aminouracil (5AU) and 6-aminouracil (6AU) in aqueous solution was studied by femtosecond fluorescence upconversion. The fluorescence ...

The peculiar spectral properties of amino-substituted uracils: a combined theoretical and experimental study.

J. Phys. Chem. B 114(39) , 12708-19, (2010)

A detailed experimental and computational study of the absorption and fluorescence spectra of 5-aminouracil (5 AU) and 6-aminouracil (6 AU) in aqueous solution is reported. The lowest energy band of t...

Recovery from the 5-AU induced blockage in interphase: evidence for differential recovery.

Cytologia 47(3-4) , 545-53, (1982)


More Articles


Related Compounds

  • 5-Aminouracil
  • 2-Thio-5-aminouracil
  • 5-aminouracil-6-sulfonic acid
  • 1,3,6-trimethyl-5-aminouracil
  • 6-(N-methylamino)-5-aminouracil
  • 6-(N-ethylanilino)-5-aminouracil
  • 3-[4-(Pentafluoroethyl)phenyl]piperidine
  • rac-3-[(1R,3R)-3-amino-2,2-dimethylcyclopropyl]-4-bromophenol
  • 3-[(4-Bromo-3-fluorophenyl)methyl]pyrrolidin-3-ol
  • 3-(2,6-Dichloropyridin-3-yl)-3,3-difluoropropan-1-amine
  • tert-butyl N-[1-(4-aminobutan-2-yl)cyclopentyl]carbamate
  • 3-Amino-2-methyl-2-(oxan-2-yl)propan-1-ol
  • tert-butyl N-[1-oxo-2-(3-phenyl-1H-pyrazol-4-yl)propan-2-yl]carbamate
  • rac-tert-butyl N-{4-[(1R,2S)-2-aminocyclopropyl]-2-chlorophenyl}carbamate
  • tert-butyl N-methyl-N-[1-(3-nitrophenyl)-2-oxoethyl]carbamate
  • 3-Amino-1-(2-methyloxolan-3-yl)cyclobutane-1-carboxylic acid
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