Z-Arg-Arg-Pro-Phe-His-Sta-Ile-His-Lys(Boc)-OMe

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Names

[ Name ]:
Z-Arg-Arg-Pro-Phe-His-Sta-Ile-His-Lys(Boc)-OMe

[Synonym ]:
L-Histidinamide, N-[(phenylmethoxy)carbonyl]-L-arginyl-L-arginyl-L-prolyl-L-phenylalanyl-N-[(1S,2S,6S,9S,12S)-2-hydroxy-9-(1H-imidazol-4-ylmethyl)-12-(methoxycarbonyl)-20,20-dimethyl-6-[(1S)-1-meth ylpropyl]-1-(2-methylpropyl)-4,7,10,18-tetraoxo-19-oxa-5,8,11,17-tetraazaheneicos-1-yl]-
N-[(Benzyloxy)carbonyl]-L-arginyl-L-arginyl-L-prolyl-L-phenylalanyl-N-[(10S,13S,16S,20S,21S)-16-[(2S)-2-butanyl]-20-hydroxy-13-(1H-imidazol-4-ylmethyl)-10-(methoxycarbonyl)-2,2,23-trimethyl-4,12,15 ,18-tetraoxo-3-oxa-5,11,14,17-tetraazatetracosan-21-yl]-L-histidinamide
MFCD00133577

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Molecular Formula ]:
C₇₂H₁₁₀N₂₀O₁₅

[ Molecular Weight ]:
1495.769

[ Exact Mass ]:
1494.845947

[ LogP ]:
2.52

[ Index of Refraction ]:
1.636

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Articles

Sustained reduction in blood pressure during chronic administration of a renin inhibitor to normotensive marmosets.

J. Cardiovasc. Pharmacol. 10 Suppl 7 , S96-8, (1987)

In this study, the hypotensive efficacy of a renin inhibitor was investigated during chronic administration. The renin inhibitor CGP 29,287 was administered by continuous intraperitoneal infusion with...

Biochemical effects of prolonged renin inhibition in marmosets.

J. Hypertens. 7(8) , 615-8, (1989)

The renin inhibitor CGP 29,287 was administered continuously for 7 days (30 mg/kg per day, intraperitoneally, via osmotic minipumps) to normotensive marmosets fed a low-salt diet. As a control, anothe...

Comparison of chronic inhibition of renin and converting enzyme in the marmoset.

Clin. Exp. Hypertens. A. 9(2-3) , 337-43, (1987)

The primate-specific renin inhibitor CGP 29287 (30 mg/kg/d, n = 5) or the converting-enzyme inhibitor CGS 14831 (30 mg/kg/d, n = 8) were administered by continuous intraperitoneal infusion via osmotic...

Z-Arg-Arg-Pro-Phe-His-Sta-Ile-His-Lys(Boc)-OMe
z-pro-phe-his-leu-leu-val-tyr-ser-4m-betana
Z-Phe-Lys
z-his-lys(boc)-nhnh2
Z-Pro-Lys(BOC)-Pro-Val-NH2
Z-HIS-LYS(BOC)-OH
4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
(4-Methyl-tetrahydro-furan-2-yl)-methanol
N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
tert-butyl N-[4-(furan-3-yl)-4-oxobutan-2-yl]carbamate
tert-Butyl-DL-alanine
4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide