Z-Arg-Arg-Pro-Phe-His-Sta-Ile-His-Lys(Boc)-OMe

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Names

[ CAS No. ]:
93287-54-8

[ Name ]:
Z-Arg-Arg-Pro-Phe-His-Sta-Ile-His-Lys(Boc)-OMe

[Synonym ]:
L-Histidinamide, N-[(phenylmethoxy)carbonyl]-L-arginyl-L-arginyl-L-prolyl-L-phenylalanyl-N-[(1S,2S,6S,9S,12S)-2-hydroxy-9-(1H-imidazol-4-ylmethyl)-12-(methoxycarbonyl)-20,20-dimethyl-6-[(1S)-1-meth ylpropyl]-1-(2-methylpropyl)-4,7,10,18-tetraoxo-19-oxa-5,8,11,17-tetraazaheneicos-1-yl]-
N-[(Benzyloxy)carbonyl]-L-arginyl-L-arginyl-L-prolyl-L-phenylalanyl-N-[(10S,13S,16S,20S,21S)-16-[(2S)-2-butanyl]-20-hydroxy-13-(1H-imidazol-4-ylmethyl)-10-(methoxycarbonyl)-2,2,23-trimethyl-4,12,15 ,18-tetraoxo-3-oxa-5,11,14,17-tetraazatetracosan-21-yl]-L-histidinamide
MFCD00133577

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Molecular Formula ]:
C72H110N20O15

[ Molecular Weight ]:
1495.769

[ Exact Mass ]:
1494.845947

[ LogP ]:
2.52

[ Index of Refraction ]:
1.636

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Articles

Sustained reduction in blood pressure during chronic administration of a renin inhibitor to normotensive marmosets.

J. Cardiovasc. Pharmacol. 10 Suppl 7 , S96-8, (1987)

In this study, the hypotensive efficacy of a renin inhibitor was investigated during chronic administration. The renin inhibitor CGP 29,287 was administered by continuous intraperitoneal infusion with...

Biochemical effects of prolonged renin inhibition in marmosets.

J. Hypertens. 7(8) , 615-8, (1989)

The renin inhibitor CGP 29,287 was administered continuously for 7 days (30 mg/kg per day, intraperitoneally, via osmotic minipumps) to normotensive marmosets fed a low-salt diet. As a control, anothe...

Comparison of chronic inhibition of renin and converting enzyme in the marmoset.

Clin. Exp. Hypertens. A. 9(2-3) , 337-43, (1987)

The primate-specific renin inhibitor CGP 29287 (30 mg/kg/d, n = 5) or the converting-enzyme inhibitor CGS 14831 (30 mg/kg/d, n = 8) were administered by continuous intraperitoneal infusion via osmotic...


More Articles

Related Compounds

  • Z-Arg-Arg-Pro-Phe-His-Sta-Ile-His-Lys(Boc)-OMe
  • z-pro-phe-his-leu-leu-val-tyr-ser-4m-betana
  • Z-Phe-Lys
  • z-his-lys(boc)-nhnh2
  • Z-Pro-Lys(BOC)-Pro-Val-NH2
  • Z-HIS-LYS(BOC)-OH
  • 9-hydroxy-7-methyl-8-[(2E)-3-(2,4,5-trimethoxyphenyl)prop-2-enoyl]-2,3-dihydrocyclopenta[c]chromen-4(1H)-one
  • N-[3-(4-carbamoylpiperidin-1-yl)-3-oxopropyl]-1,3,4,9-tetrahydro-2H-beta-carboline-2-carboxamide
  • (4,6-dimethoxy-1-methyl-1H-indol-2-yl)(8-methoxy-1,3,4,5-tetrahydro-2H-pyrido[4,3-b]indol-2-yl)methanone
  • 2-[(1'-acetyl-4-oxo-3,4-dihydrospiro[chromene-2,4'-piperidin]-7-yl)oxy]-N-(3,4-dimethoxybenzyl)acetamide
  • methyl 1-[N-(1,3,4,9-tetrahydro-2H-beta-carbolin-2-ylcarbonyl)-beta-alanyl]piperidine-4-carboxylate
  • N-(2-(1H-indol-3-yl)ethyl)-3-(7-methoxy-2-oxo-4-phenyl-2H-chromen-6-yl)propanamide
  • N-{3-[(3-hydroxyphenyl)amino]-3-oxopropyl}-1,3,4,9-tetrahydro-2H-beta-carboline-2-carboxamide
  • 6-bromo-2-(3-methoxybenzoyl)-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole
  • 2-[2-(4-isopropylphenyl)-1,3-thiazol-4-yl]-N-[2-(5-methoxy-1H-indol-3-yl)ethyl]acetamide
  • 2-benzoyl-6-bromo-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole
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