esatenolol

Suppliers

Names

[ CAS No. ]:
93379-54-5

[ Name ]:
esatenolol

[Synonym ]:
(-)-4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]benzeneacetamide
S-(-)-Atenolol
(S)-4-[2-hydroxy-3-((1-methylethyl)amino)propoxy]benzeneacetamide
MFCD00074918
(-)-Atenolol
1-Phenylbiguanide hydrochloride
2-[4-[(2S)-2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]acetamide
Esatenolol [INN]
4-{(2S)-2-hydroxy-3-[(1-methylethyl)amino]propoxy}benzeneacetamide
Esatenolol

Chemical & Physical Properties

[ Density]:
1.125 g/cm3

[ Boiling Point ]:
508ºC at 760mmHg

[ Melting Point ]:
148-152 ºC(lit.)

[ Molecular Formula ]:
C14H22N2O3

[ Molecular Weight ]:
266.33600

[ Flash Point ]:
261.1ºC

[ Exact Mass ]:
266.16300

[ PSA ]:
84.58000

[ LogP ]:
1.54330

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
CY1488020
CHEMICAL NAME :
Benzeneacetamide, 4-(2-hydroxy-3-((1-methylethyl)amino)propoxy)-, (S)-
CAS REGISTRY NUMBER :
93379-54-5
LAST UPDATED :
199403
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C14-H22-N2-O3
MOLECULAR WEIGHT :
266.38

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
97 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PIXXD2 PCT (Patent Cooperation Treaty) International Application. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #91-10428

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
CY1488020

[ HS Code ]:
2924299090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • isopropylamine
  • 4-[(2S)-2-Oxiranylmethoxy]benzeneacetamide
  • p-hydroxyphenylacetamide
  • (S)-Glycidyl nosylate
  • Epichlorohydrin
  • 4-Hydroxyphenylacetic acid
  • butyl p-hydroxyphenylacetate

DownStream

Customs

[ HS Code ]: 2924299090

[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

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Related Compounds

  • 3-(4-(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)piperidine-1-carbonyl)-1-methylpyridin-2(1H)-one
  • benzo[d]thiazol-2-yl(4-(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)piperidin-1-yl)methanone
  • 1-(4-(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)piperidin-1-yl)-2-((4-fluorophenyl)thio)ethanone
  • 4-[4-(Quinolin-2-Yl)-1h-1,2,3-Triazol-1-Yl]phenol
  • 4-{4-[6-(2-Methoxyethoxy)quinolin-2-Yl]-1h-1,2,3-Triazol-1-Yl}phenol
  • Norbolethone, (-)-
  • Benzo(10,11)chryseno(3,4-b)oxirene-7,8-diol, 7,8,8a,9a-tetrahydro-8a,9a-t2-, (7alpha,8beta,8abeta,9abeta)-(+-)-
  • 3-(2-bromophenyl)-1-(4-(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)piperidin-1-yl)propan-1-one
  • 7-(N-(2S-Hydroxy-2-(4-fluorophenyloxy)ethylcarbonyl)-2-amino-3,5-dihydroxycyclopentyl)-5-heptenoic acid
  • 6-(4-(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)piperidine-1-carbonyl)-2-methylpyridazin-3(2H)-one
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