Conantokin G

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Names

[ CAS No. ]:
93438-65-4

[ Name ]:
Conantokin G

[Synonym ]:
'SLEEPER PEPTIDE'
H-GLY-GLU-GLA-GLA-LEU-GLN-GLA-ASN-GLN-GLA-LEU-ILE-ARG-GLA-LYS-SER-ASN-NH2
conotoxin GV
M.W. 2264.1 C88H138N26O44
GLY-GLU-GLA-GLA-LEU-GLN-GLA-ASN-GLN-GLA-LEU-ILE-ARG-GLA-LYS-SER-ASN-NH2
Conotoxin GV,Sleeper Peptide

Chemical & Physical Properties

[ Molecular Formula ]:
C88H138N26O44

[ Molecular Weight ]:
2264.19000

[ Exact Mass ]:
2262.94000

[ PSA ]:
1225.52000

[ Storage condition ]:
-20°C

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ RIDADR ]:
NONH for all modes of transport

Articles

NMDA/NR2B selective antagonists in the treatment of ischemic brain injury.

Curr. Drug Targets. CNS Neurol. Disord. 4(2) , 143-51, (2005)

Glutamate is the main excitatory neurotransmitter in the central nervous system and it plays a significant role not only in synaptic transmission but also in acute and chronic neuropathologies includi...

The effect of CGX-1007 and CI-1041, novel NMDA receptor antagonists, on NMDA receptor-mediated EPSCs.

Epilepsy Res. 59(1) , 13-24, (2004)

The N-methyl-D-aspartate (NMDA) receptor-gated ion channel is comprised of at least one NR1 subunit and any of four NR2 subunits (NR2A-D). The NR2 subunit confers different pharmacological and kinetic...

The selectivity of conantokin-G for ion channel inhibition of NR2B subunit-containing NMDA receptors is regulated by amino acid residues in the S2 region of NR2B.

Neuropharmacology 57(2) , 127-36, (2009)

The conantokins are short, naturally occurring peptides that inhibit ion flow through N-methyl-d-aspartate receptor (NMDAR) channels. One member of this peptide family, conantokin-G (con-G), shows hig...


More Articles

Related Compounds

  • CONANTOKIN G FREE ACID
  • conantokin R
  • Gancaonin G
  • luffariolide G
  • Benzenebutanenitrile, g-(1-methylethoxy)-
  • Palavit G
  • 1-(4-Ethyl-4-hydroxypiperidin-1-yl)-3,3,3-trifluoropropan-1-one
  • 1-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(trifluoromethyl)cyclobutane-1-carboxylic acid
  • 6-(tert-Butyl) 2,4-diethyl 7,8-dihydropyrido[4,3-d]pyrimidine-2,4,6(5H)-tricarboxylate
  • 2-Formyl-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazole-3-carboxylic acid
  • tert-Butyl 1-methyl-9-oxo-3-azaspiro[5.5]undecane-3-carboxylate
  • tert-Butyl 3-((thietan-3-ylamino)methyl)pyrrolidine-1-carboxylate
  • 3-Bromo-7-chloro-2-methylpyrazolo[1,5-a]pyrimidine-5-carbaldehyde
  • 4-(Difluoromethoxy)-2-methylpiperidine hydrochloride
  • 4-(Difluoromethoxy)-2-methylpiperidine
  • tert-Butyl 7-(1-hydroxyethyl)-3,4-dihydroquinoline-1(2H)-carboxylate
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