Conantokin G

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Names

[ CAS No. ]:
93438-65-4

[ Name ]:
Conantokin G

[Synonym ]:
'SLEEPER PEPTIDE'
H-GLY-GLU-GLA-GLA-LEU-GLN-GLA-ASN-GLN-GLA-LEU-ILE-ARG-GLA-LYS-SER-ASN-NH2
conotoxin GV
M.W. 2264.1 C88H138N26O44
GLY-GLU-GLA-GLA-LEU-GLN-GLA-ASN-GLN-GLA-LEU-ILE-ARG-GLA-LYS-SER-ASN-NH2
Conotoxin GV,Sleeper Peptide

Chemical & Physical Properties

[ Molecular Formula ]:
C88H138N26O44

[ Molecular Weight ]:
2264.19000

[ Exact Mass ]:
2262.94000

[ PSA ]:
1225.52000

[ Storage condition ]:
-20°C

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ RIDADR ]:
NONH for all modes of transport

Articles

NMDA/NR2B selective antagonists in the treatment of ischemic brain injury.

Curr. Drug Targets. CNS Neurol. Disord. 4(2) , 143-51, (2005)

Glutamate is the main excitatory neurotransmitter in the central nervous system and it plays a significant role not only in synaptic transmission but also in acute and chronic neuropathologies includi...

The effect of CGX-1007 and CI-1041, novel NMDA receptor antagonists, on NMDA receptor-mediated EPSCs.

Epilepsy Res. 59(1) , 13-24, (2004)

The N-methyl-D-aspartate (NMDA) receptor-gated ion channel is comprised of at least one NR1 subunit and any of four NR2 subunits (NR2A-D). The NR2 subunit confers different pharmacological and kinetic...

The selectivity of conantokin-G for ion channel inhibition of NR2B subunit-containing NMDA receptors is regulated by amino acid residues in the S2 region of NR2B.

Neuropharmacology 57(2) , 127-36, (2009)

The conantokins are short, naturally occurring peptides that inhibit ion flow through N-methyl-d-aspartate receptor (NMDAR) channels. One member of this peptide family, conantokin-G (con-G), shows hig...


More Articles


Related Compounds

  • CONANTOKIN G FREE ACID
  • conantokin R
  • Gancaonin G
  • luffariolide G
  • Benzenebutanenitrile, g-(1-methylethoxy)-
  • Palavit G
  • Ethyl 3-[3-(1-amino-4,4-dimethylcyclohexyl)-1,2,4-oxadiazol-5-yl]propanoate
  • Tert-butyl 3-[3-(1-amino-4-tert-butylcyclohexyl)-1,2,4-oxadiazol-5-yl]propanoate
  • Tert-butyl 3-[3-(4-aminothian-4-yl)-1,2,4-oxadiazol-5-yl]propanoate
  • Tert-butyl 3-[3-(3-aminooxan-3-yl)-1,2,4-oxadiazol-5-yl]propanoate
  • Methyl 4-{8-hydroxy-2-azabicyclo[3.3.1]nonan-8-yl}oxane-4-carboxylate
  • 2-[(3aR,7aS)-3a,7a-bis(hydroxymethyl)-octahydro-1H-isoindol-2-yl]acetic acid
  • tert-butyl (2E)-3-(5-fluoro-2-methylphenyl)prop-2-enoate
  • Tert-butyl 4-(2,4-dichlorophenyl)pyrrolidine-3-carboxylate
  • Tert-butyl 4-(3-methoxyphenyl)pyrrolidine-3-carboxylate
  • Tert-butyl 4-(3-methylphenyl)pyrrolidine-3-carboxylate
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