Lumacaftor (VX-809)

Suppliers

Names

[ CAS No. ]:
936727-05-8

[ Name ]:
Lumacaftor (VX-809)

[Synonym ]:
3-[6-({[1-(2,2-difluoro-1,3-benzodioxol-5-yl)cyclopropyl]carbonyl}amino)-3- methylpyridin-2-yl]benzoic acid
VX-809 (Lumacaftor)
3-(6-{[1-(2,2-Difluoro-benzo[1,3]dioxol-5-yl)-cyclopropanecarbonyl]-amino}-3-methyl-pyridin-2-yl)-benzoic acid
MFCD16659051
benzoic acid, 3-[6-[[[1-(2,2-difluoro-1,3-benzodioxol-5-yl)cyclopropyl]carbonyl]amino]-3-methyl-2-pyridinyl]-
3-[6-({[1-(2,2-Difluoro-1,3-benzodioxol-5-yl)cyclopropyl]carbonyl}amino)-3-methylpyridin-2-yl]benzoic acid
Lumacaftor
3-[6-({[1-(2,2-Difluoro-1,3-benzodioxol-5-yl)cyclopropyl]carbonyl}amino)-3-methyl-2-pyridinyl]benzoic acid
Lumacaftorum
UNII-EGP8L81APK
3-(6-(1-(2,2-Difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid
VX-809
VX809
3-[6-[[[1-(2,2-Difluoro-1,3-benzodioxol-5-yl)cyclopropyl]carbonyl]amino]-3-methyl-2-pyridinyl]benzoic acid

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
653.0±55.0 °C at 760 mmHg

[ Molecular Formula ]:
C24H18F2N2O5

[ Molecular Weight ]:
452.407

[ Flash Point ]:
348.7±31.5 °C

[ Exact Mass ]:
452.118378

[ PSA ]:
97.75000

[ LogP ]:
5.77

[ Vapour Pressure ]:
0.0±2.1 mmHg at 25°C

[ Index of Refraction ]:
1.670

Related Compounds

  • 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarboxamido)-3-methylpyridin-2-yl)-t-butylbenzoate
  • Lumacaftor-d4
  • Telaprevir (VX-950)
  • VX853
  • Tozasertib
  • Tezacaftor(VX-661)
  • Methyl 3-(3,4-dimethoxyphenyl)benzoate
  • 5-fluoro-3,4-dihydro-2H-1-benzopyran
  • (2s,4r)-1-(6-Aminohexanoyl)-4-hydroxy-2-(4,4'-dimethoxytrityloxymethyl)pyrrolidine
  • 1-(4-Bromo-2-methoxyphenoxy)-2-methylpropan-2-ol
  • 1-(4-Amino-2-methoxyphenoxy)-2-methylpropan-2-ol
  • tert-butyl N-(4-hydroxyphenyl)-N-phenylcarbamate
  • 2-fluoro-N-{[2-(2,2,2-trifluoroethoxy)pyridin-3-yl]methyl}pyridine-4-carboxamide
  • N-(4-bromo-2-methylphenyl)-2-fluoro-N-methylpyridine-4-carboxamide
  • 4-(4-chloro-2-methylphenyl)-6,7-dihydro-5H-pyrrolo[3,4-d]pyrimidin-2-amine
  • 2-Amino-N-cyclopropyl-4-(2,4-dichloro-5-hydroxyphenyl)-5,7-dihydro-6H-pyrrolo[3,4-d]pyrimidine-6-carboxamide