Adenosine 5'-[γ-thio]triphosphate Tetralithium Salt

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Names

[ Name ]:
Adenosine 5'-[γ-thio]triphosphate Tetralithium Salt

[Synonym ]:
Tetralithium 5'-O-[({[(dioxidophosphorothioyl)oxy]phosphinato}oxy)phosphinato]adenosine
Adenosine, 5'-O-[hydroxy[[hydroxy[(hydroxymercaptophosphinyl)oxy]phosphinyl]oxy]phosphinyl]-, lithium salt (1:4)

Chemical & Physical Properties

[ Boiling Point ]:
940.5ºC at 760 mmHg

[ Molecular Formula ]:
C₁₀H₁₂Li₄N₅O₁₂P₃S

[ Molecular Weight ]:
546.979

[ Flash Point ]:
522.6ºC

[ Exact Mass ]:
547.005615

[ PSA ]:
334.90000

[ LogP ]:
1.47200

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
26-36

[ RIDADR ]:
NONH for all modes of transport

Articles

Specific inhibition of p97/VCP ATPase and kinetic analysis demonstrate interaction between D1 and D2 ATPase domains.

J. Mol. Biol. 426(15) , 2886-99, (2014)

The p97 AAA (ATPase associated with diverse cellular activities), also called VCP (valosin-containing protein), is an important therapeutic target for cancer and neurodegenerative diseases. p97 forms ...

The enzymatic synthesis of thiophosphate analogs of nucleotides.

Biochim. Biophys. Acta 276 , 155, (1972)

ATP binds to proteasomal ATPases in pairs with distinct functional effects, implying an ordered reaction cycle.

Cell 144 , 526-538, (2011)

In the eukaryotic 26S proteasome, the 20S particle is regulated by six AAA ATPase subunits and, in archaea, by a homologous ring complex, PAN. To clarify the role of ATP in proteolysis, we studied how...