KU-0063794

Suppliers

Names

[ Name ]:
KU-0063794

[Synonym ]:
KU-0063794
(5-{2-[(2R,6S)-2,6-Dimethyl-4-morpholinyl]-4-(4-morpholinyl)pyrido[2,3-d]pyrimidin-7-yl}-2-methoxyphenyl)methanol
(5-{2-[(2R,6S)-2,6-dimethylmorpholin-4-yl]-4-(morpholin-4-yl)pyrido[2,3-d]pyrimidin-7-yl}-2-methoxyphenyl)methanol
Benzenemethanol, 5-[2-[(2R,6S)-2,6-dimethyl-4-morpholinyl]-4-(4-morpholinyl)pyrido[2,3-d]pyrimidin-7-yl]-2-methoxy-
Benzenemethanol, 5-[2-[(2R,6S)-2,6-dimethyl-4-morpholinyl]-4-(4-morpholinyl)pyrido[2,3-d]pyrimidin-7-yl]-2-methoxy-, rel-
ku 0063794
KU0063794

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
694.3±65.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂₅H₃₁N₅O₄

[ Molecular Weight ]:
465.545

[ Flash Point ]:
373.7±34.3 °C

[ Exact Mass ]:
465.237610

[ PSA ]:
93.07000

[ LogP ]:
0.27

[ Appearance of Characters ]:
white to beige

[ Vapour Pressure ]:
0.0±2.3 mmHg at 25°C

[ Index of Refraction ]:
1.609

[ Storage condition ]:
Store at RT

[ Water Solubility ]:
DMSO: >2mg/mL (warmed)

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H301

[ Precautionary Statements ]:
P301 + P310

[ Hazard Codes ]:
T

[ Risk Phrases ]:
25

[ Safety Phrases ]:
45

[ RIDADR ]:
UN 2811 6.1 / PGIII

Articles

Mechanistic target of rapamycin inhibition extends cellular lifespan in dendritic cells by preserving mitochondrial function.

J. Immunol. 193(6) , 2821-30, (2014)

TLR-mediated activation of dendritic cells (DCs) is associated with a metabolic transition in which mitochondrial oxidative phosphorylation is inhibited by endogenously synthesized NO and the cells be...