Dimethocaine
Suppliers
Names
[ CAS No. ]:
94-15-5
[ Name ]:
Dimethocaine
[Synonym ]:
Larocaine
1-Propanol, 3-(diethylamino)-2,2-dimethyl-, p-aminobenzoate (ester) (8CI)
1-Propanol, 3-(diethylamino)-2,2-dimethyl-, 4-aminobenzoate (ester)
1-Aminobenzoyl-2,2-dimethyl-3-diethylaminopropanol
3-(Diethylamino)-2,2-dimethyl-1-propanol p-Aminobenzoate
3-(Diethylamino)-2,2-dimethylpropyl 4-aminobenzoate
p-Aminobenzoate of Diethylaminoneopentyl Alcohol
3-Diethylamino-2,2-dimethylpropyl p-Aminobenzoate
Dimethocaine
1-Propanol, 3- (diethylamino)-2,2-dimethyl-, p-aminobenzoate (ester)
DiMethocine
1-Propanol, 3-(diethylamino)-2,2-dimethyl-, 4-aminobenzoate (ester) (9CI)
1-Propanol, 3- (diethylamino)-2,2-dimethyl-, 4-aminobenzoate (ester)
3-Diethylamino-2,2-dimethylpropyl 4-aminobenzoate
Chemical & Physical Properties
[ Density]:
1.0±0.1 g/cm3
[ Boiling Point ]:
403.5±25.0 °C at 760 mmHg
[ Melting Point ]:
53.0 to 57.0 deg-C
[ Molecular Formula ]:
C16H26N2O2
[ Molecular Weight ]:
278.390
[ Flash Point ]:
197.8±23.2 °C
[ Exact Mass ]:
278.199432
[ PSA ]:
55.56000
[ LogP ]:
3.55
[ Vapour Pressure ]:
0.0±0.9 mmHg at 25°C
[ Index of Refraction ]:
1.529
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- UB1575000
- CHEMICAL NAME :
- 1-Propanol, 3-(diethylamino)-2,2-dimethyl-, p-aminobenzoate
- CAS REGISTRY NUMBER :
- 94-15-5
- BEILSTEIN REFERENCE NO. :
- 2215967
- LAST UPDATED :
- 199712
- DATA ITEMS CITED :
- 7
- MOLECULAR FORMULA :
- C16-H26-N2-O2
- MOLECULAR WEIGHT :
- 278.44
- WISWESSER LINE NOTATION :
- ZR DVO1X1&1&1N2&2
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 380 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold Cardiac - other changes Lungs, Thorax, or Respiration - other changes
- REFERENCE :
- AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. (Berlin, Ger.) V.110-253, 1925-66. For publisher information, see NSAPCC. Volume(issue)/page/year: 168,447,1932
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 40 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- PHREA7 Physiological Reviews. (American Physiological Soc., 9650 Rockville Pike, Bethesda, MD 20814) V.1- 1921- Volume(issue)/page/year: 12,190,1932
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 150 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- PHREA7 Physiological Reviews. (American Physiological Soc., 9650 Rockville Pike, Bethesda, MD 20814) V.1- 1921- Volume(issue)/page/year: 12,190,1932
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 150 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- PHREA7 Physiological Reviews. (American Physiological Soc., 9650 Rockville Pike, Bethesda, MD 20814) V.1- 1921- Volume(issue)/page/year: 12,190,1932
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 200 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- PHREA7 Physiological Reviews. (American Physiological Soc., 9650 Rockville Pike, Bethesda, MD 20814) V.1- 1921- Volume(issue)/page/year: 12,190,1932
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Parenteral
- SPECIES OBSERVED :
- Amphibian - frog
- DOSE/DURATION :
- 860 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - respiratory stimulation Lungs, Thorax, or Respiration - other changes
- REFERENCE :
- AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. (Berlin, Ger.) V.110-253, 1925-66. For publisher information, see NSAPCC. Volume(issue)/page/year: 168,447,1932 *** REVIEWS *** TOXICOLOGY REVIEW PHREA7 Physiological Reviews. (American Physiological Soc., 9650 Rockville Pike, Bethesda, MD 20814) V.1- 1921- Volume(issue)/page/year: 12,190,1932
Safety Information
[ HS Code ]:
2942000000
Customs
[ HS Code ]: 2922499990
[ Summary ]:
HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%