Sodium [(4-aminobenzoyl)amino]acetate

Suppliers

Names

[ CAS No. ]:
94-16-6

[ Name ]:
Sodium [(4-aminobenzoyl)amino]acetate

[Synonym ]:
Sodium [(4-aminobenzoyl)amino]acetate
P-AMINOHIPPURIC ACID SODIUM SALT
Glycine, N-(4-aminobenzoyl)-, sodium salt (1:1)
EINECS 202-309-8
Sodium 2-amino-2-benzamidoacetate
MFCD00044689
Aminohippurate (sodium)

Chemical & Physical Properties

[ Boiling Point ]:
517.2ºC at 760 mmHg

[ Melting Point ]:
123-125°C

[ Molecular Formula ]:
C9H9N2NaO3

[ Molecular Weight ]:
216.169

[ Flash Point ]:
266.6ºC

[ Exact Mass ]:
216.051086

[ PSA ]:
95.25000

[ Storage condition ]:
2-8℃

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
MR8157200
CHEMICAL NAME :
Hippuric acid, p-amino-, monosodium salt
CAS REGISTRY NUMBER :
94-16-6
LAST UPDATED :
199712
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C9-H9-N2-O3.Na
MOLECULAR WEIGHT :
216.19
WISWESSER LINE NOTATION :
ZR DVM1VQ &-NA-

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
4075 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: -,828,1990
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
4930 mg/kg
TOXIC EFFECTS :
Peripheral Nerve and Sensation - spastic paralysis with or without sensory change Behavioral - muscle contraction or spasticity Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 84,147,1945

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Safety Phrases ]:
S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
MR8157200

[ HS Code ]:
2924299090

Customs

[ HS Code ]: 2924299090

[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

Balanced Hydroxyethylstarch (HES 130/0.4) Impairs Kidney Function In-Vivo without Inflammation.

PLoS ONE 10 , e0137247, (2015)

Volume therapy is a standard procedure in daily perioperative care, and there is an ongoing discussion about the benefits of colloid resuscitation with hydroxyethylstarch (HES). In sepsis HES should b...

Flavonoid conjugates interact with organic anion transporters (OATs) and attenuate cytotoxicity of adefovir mediated by organic anion transporter 1 (OAT1/SLC22A6).

Biochem. Pharmacol. 81 , 942-949, (2011)

Flavonoids are conjugated by phase II enzymes in humans to form glucuronidated and sulfated metabolites that are excreted in urine via the kidney. In this study, we examined the interaction between me...

Molecular evidence for an involvement of organic anion transporters (OATs) in aristolochic acid nephropathy.

Toxicology 264 , 74-79, (2009)

Aristolochic acid (AA), present in Aristolochia species, is the major causative agent in the development of severe renal failure and urothelial cancers in patients with AA nephropathy. It may also be ...


More Articles

Related Compounds

  • Sodium [(4-aminobenzoyl)amino]acetate hydrate (1:1:1)
  • METHYL [(4-AMINOBENZOYL)AMINO]ACETATE HYDROCHLORIDE
  • sodium (4-hydroxyphenyl)[(phenylacetyl)amino]acetate
  • sodium (4-hydroxyphenyl)[(3-methoxy-1-methyl-3-oxoprop-1-enyl)amino]acetate
  • sodium 7-[(4-aminobenzoyl)amino]-4-hydroxynaphthalene-2-sulphonate
  • sodium 7-[(4-aminobenzoyl)amino]-4-hydroxy-3-[(2-methoxyphenyl)azo]naphthalene-2-sulphonate
  • Methyl 4-(2-(((1-(2-(methylthio)benzyl)piperidin-4-yl)methyl)amino)-2-oxoacetamido)benzoate
  • 2-((5-(3-nitrophenyl)-1-(3-(trifluoromethyl)phenyl)-1H-imidazol-2-yl)thio)-1-(pyrrolidin-1-yl)ethanone
  • N1-((1-(2-(methylthio)benzyl)piperidin-4-yl)methyl)-N2-(4-(trifluoromethoxy)phenyl)oxalamide
  • N1-(isoxazol-3-yl)-N2-((1-(1-methyl-2-oxo-1,2-dihydropyridine-3-carbonyl)piperidin-4-yl)methyl)oxalamide
  • N1-cyclopropyl-N2-((1-(2-(methylthio)nicotinoyl)piperidin-4-yl)methyl)oxalamide
  • N1-((1-(2-(methylthio)nicotinoyl)piperidin-4-yl)methyl)-N2-(pyridin-3-yl)oxalamide
  • N1-(furan-2-ylmethyl)-N2-((1-(2-(methylthio)nicotinoyl)piperidin-4-yl)methyl)oxalamide
  • N1-(5-methylisoxazol-3-yl)-N2-((1-(2-(methylthio)nicotinoyl)piperidin-4-yl)methyl)oxalamide
  • N1-(2-methoxyphenyl)-N2-((1-(2-(methylthio)nicotinoyl)piperidin-4-yl)methyl)oxalamide
  • N1-(4-fluorobenzyl)-N2-((1-(2-(methylthio)nicotinoyl)piperidin-4-yl)methyl)oxalamide