3-(Phenylazo)-2,6-pyridinediamine

Suppliers

Names

[ CAS No. ]:
94-78-0

[ Name ]:
3-(Phenylazo)-2,6-pyridinediamine

[Synonym ]:
Baridium
Pyridium
3-Phenylazo-pyridin-2,6-diyldiamin
Viridium
2,6-diamino-3-(phenylazo)pyridine
Sedural
Pyridiate
Gastracid
Urodine
3-phenylazo-pyridine-2,6-diamine
Urogesic
Geridium
3-phenyldiazenylpyridine-2,6-diamine

Chemical & Physical Properties

[ Density]:
1.32g/cm3

[ Boiling Point ]:
442.3ºC at 760mmHg

[ Melting Point ]:
235 - 240ºC

[ Molecular Formula ]:
C11H11N5

[ Molecular Weight ]:
213.23900

[ Exact Mass ]:
213.10100

[ PSA ]:
89.65000

[ LogP ]:
3.82380

[ Index of Refraction ]:
1.6880 (estimate)

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
US7700000
CHEMICAL NAME :
Pyridine, 2,6-diamino-3-(phenylazo)-
CAS REGISTRY NUMBER :
94-78-0
BEILSTEIN REFERENCE NO. :
0184497
LAST UPDATED :
199612
DATA ITEMS CITED :
6
MOLECULAR FORMULA :
C11-H11-N5
MOLECULAR WEIGHT :
213.27
WISWESSER LINE NOTATION :
T6NJ BZ CNUNR& FZ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
560 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - structural or functional change in trachea or bronchi Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 51,200,1934
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
580 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PAHEAA Pharmaceutica Acta Helvetiae. (Schweizerische Apothekerzeitung, Postfach 3006, CH3000 Bern, 7, Switzerland) V.1- 1926- Volume(issue)/page/year: 35,423,1960 ** TUMORIGENIC DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Implant
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
80 mg/kg
TOXIC EFFECTS :
Tumorigenic - neoplastic by RTECS criteria Kidney, Ureter, Bladder - tumors
REFERENCE :
BJCAAI British Journal of Cancer. (Macmillan Press Ltd., Houndmills, Basingstoke, Hants. RG21 2XS, UK) V.1- 1947- Volume(issue)/page/year: 11,212,1957 *** REVIEWS *** IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 8,117,1975 IARC Cancer Review:Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 8,117,1975 TOXICOLOGY REVIEW AEHLAU Archives of Environmental Health. (Heldref Pub., 4000 Albemarle St., NW, Washington, DC 20016) V.1- 1960- Volume(issue)/page/year: 23,6,1971

Safety Information

[ Hazard Codes ]:
Xi

[ HS Code ]:
2933399090

Synthetic Route

Precursor & DownStream

Precursor

  • Phenazopyridine hydrochloride
  • Benzenediazonium chloride

DownStream

  • pyridine-2,3,6-triamine
  • Benzenesulfonamide,4-[2-[2,6-diamino-5-(2-phenyldiazenyl)-3-pyridinyl]diazenyl]-N-2-thiazolyl-

Customs

[ HS Code ]: 2933399090

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%


Related Compounds

  • Phenazopyridine hydrochloride
  • 3-Nitro-2,6-pyridinediamine
  • 3-Bromo-2,6-pyridinediamine
  • 3-Bromo-2,6-pyridinediamine
  • 3-Methoxy-2,6-pyridinediamine
  • 3-(phenylazo)toluene-2,6-diamine monohydrochloride
  • 3-[(4-bromophenyl)sulfonyl]-N-(4-ethylphenyl)thieno[2,3-e][1,2,3]triazolo[1,5-a]pyrimidin-5-amine
  • Methyl 4-[(2-benzoyl-4-chlorophenyl)carbamoyl]benzoate
  • N-{5-chloro-2-[4-(phenylcarbonyl)piperazin-1-yl]phenyl}acetamide
  • (3R)-N-ethyl-1,2,3,4-tetrahydroisoquinoline-3-carboxamide
  • 5-(1-Chloroethyl)-3-(4-methoxyphenyl)-1,2,4-oxadiazole
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol