4-chloro-7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-d]pyrimidine

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Names

[ CAS No. ]:
941685-26-3

[ Name ]:
4-chloro-7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-d]pyrimidine

[Synonym ]:
2-[(4-chloropyrrolo[2,3-d]pyrimidin-7-yl)methoxy]ethyl-trimethylsilane
4-Chloro-7-{[2-(trimethylsilyl)ethoxy]methyl}-7H-pyrrolo[2,3-d]pyrimidine
7H-Pyrrolo[2,3-d]pyrimidine, 4-chloro-7-[[2-(trimethylsilyl)ethoxy]methyl]-

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
368.3±37.0 °C at 760 mmHg

[ Molecular Formula ]:
C12H18ClN3OSi

[ Molecular Weight ]:
283.829

[ Flash Point ]:
176.6±26.5 °C

[ Exact Mass ]:
283.090759

[ PSA ]:
39.94000

[ LogP ]:
3.13

[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C

[ Index of Refraction ]:
1.554

Synthetic Route

Precursor & DownStream

Precursor

  • [2-(Chloromethoxy)ethyl](trimethyl)silane
  • 4-Chloro-7H-pyrrolo[2,3-d]pyrimidine
  • 6-Amino-5-(2,2-diethoxyethyl)pyrimidin-4-ol
  • Pyrrolo[2,3-d]pyrimidin-4-ol

DownStream

  • INCB032304

Related Compounds

  • 1-(2-hydroxy-2-phenylethyl)-N-(2-methylphenyl)-1H-1,2,4-triazole-3-carboxamide
  • 1-(2-hydroxy-2-phenylethyl)-N-(2-phenylethyl)-1H-1,2,4-triazole-3-carboxamide
  • N-benzyl-1-(2-hydroxy-2-phenylethyl)-N-methyl-1H-1,2,4-triazole-3-carboxamide
  • N-(2-cyclohex-1-en-1-ylethyl)-1-(2-hydroxy-2-phenylethyl)-1H-1,2,4-triazole-3-carboxamide
  • 1-(2-hydroxy-2-phenylethyl)-N-(4-methoxyphenyl)-1H-1,2,4-triazole-3-carboxamide
  • 1-(2-hydroxy-2-phenylethyl)-N-(3-methoxyphenyl)-1H-1,2,4-triazole-3-carboxamide
  • 1-(2-hydroxy-2-phenylethyl)-N-(2-thienylmethyl)-1H-1,2,4-triazole-3-carboxamide
  • N-(2-fluorobenzyl)-1-(2-hydroxy-2-phenylethyl)-1H-1,2,4-triazole-3-carboxamide
  • 2-{3-[4-(2-methylphenyl)piperazine-1-carbonyl]-1H-1,2,4-triazol-1-yl}-1-phenylethan-1-ol
  • 4-(2-Bromo-4-methylphenyl)butanal
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