Lixazinone

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Names

[ CAS No. ]:
94192-59-3

[ Name ]:
Lixazinone

[Synonym ]:
Lixazinonum [Latin]
Butanamide,N-cyclohexyl-N-methyl-4-((1,2,3,5-tetrahydro-2-oxoimidazo(2,1-b)quinazolin-7-yl)oxy)
Lixazinonum
Butanamide,N-cyclohexyl-N-methyl-4-((2-oxo-1,2,3,5-tetrahydroimidazo(2,1-b)quinazolin-7-yl)oxy)
Lixazinone
N-cyclohexyl-N-methyl-4-(2-oxo-1,2,3,5-tetrahydroimidazo[2,1-b]quinazolin-7-yl)oxybutyramide
Lixazinona
Lixazinona [Spanish]
Lixazinone [INN]

Chemical & Physical Properties

[ Density]:
1.33g/cm3

[ Boiling Point ]:
579.2ºC at 760 mmHg

[ Molecular Formula ]:
C21H28N4O3

[ Molecular Weight ]:
384.47200

[ Flash Point ]:
304.1ºC

[ Exact Mass ]:
384.21600

[ PSA ]:
74.24000

[ LogP ]:
2.27190

[ Index of Refraction ]:
1.659

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
EJ3510100
CHEMICAL NAME :
Butanamide, N-cyclohexyl-N-methyl-4-((2-oxo-1,2,3,5-tetrahydroimi dazo(2,1-b)quinazolin -7-yl) oxy)-
CAS REGISTRY NUMBER :
94192-59-3
LAST UPDATED :
199806
DATA ITEMS CITED :
2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>1500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #4663320
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>1500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #4663320

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • N-Methylcyclohexanamine
  • 5-Hydroxy-2-nitrobenzaldehyde
  • ethyl 2-((5-(4-(cyclohexyl(methyl)amino)-4-oxobutoxy)-2-nitrobenzyl)amino)acetate
  • 4-(3-FORMYL-4-NITRO-PHENOXY)-BUTYRIC ACID

DownStream

Related Compounds

  • LIXAZINONE SULFATE
  • Lixazinone sulfate (USAN)
  • Acetamide, n-(7-chloro-4-quinolinyl)-
  • 3-Hydroxy-2-(4-methoxyphenyl)cyclopent-1-ene-1-carboxylic acid
  • 1H-Indole, 3,3a(2)-[4-(4-chlorophenyl)-2,6-pyridinediyl]bis-
  • (r)-2-Amino-5-(pyrimidin-5-yl)pentanoic acid
  • (s)-2-Amino-3-(2,6-difluoro-3-hydroxyphenyl)propanoic acid
  • L-Tryptophan, 4-bromo-N-[(1,1-dimethylethoxy)carbonyl]-, methyl ester
  • Benzeneacetic acid, 4-cyano-2,6-difluoro-I+/--hydroxy-
  • 4-(3-Ethoxy-4-hydroxyphenyl)pyrrolidin-2-one
  • Methyl 5-amino-2-fluoro-4-(methylsulfanyl)benzoate
  • Ethyl 3,4-dichloro-I(2)-cyano-I+/--oxobenzenepropanoate
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