2-Methyl-2-propanyl {(2S)-1-azido-3-[(3R)-tetrahydro-2H-pyran-3-y l]-2-propanyl}methylcarbamate

Names

[ CAS No. ]:
942145-26-8

[ Name ]:
2-Methyl-2-propanyl {(2S)-1-azido-3-[(3R)-tetrahydro-2H-pyran-3-y l]-2-propanyl}methylcarbamate

[Synonym ]:
tert-butyl (S)-1-azido-3-((R)-tetrahydro-2H-pyran-3-yl)propan-2-yl(methyl)carbamate
tert-butyl (S)-1-[(2R,3S)-3-(tert-butyldiphenylsilyloxy)-1-(diphenylphosphino)butan-2-ylamino]-3,3-dimethyl-1-oxobutan-2-ylcarbamate
N-(tert-Butoxycarbonyl)-L-tert-leucine N-[(2R,3S)-3-(tert-Butyldiphenylsilyloxy)-1-(diphenylphosphino)-2-butyl]amide
N-Boc-L-tert-leucine N-[(2R,3S)-3-(tert-Butyldiphenylsilyloxy)-1-(diphenylphosphino)-2-butyl]amide

Chemical & Physical Properties

[ Molecular Formula ]:
C14H26N4O3

[ Molecular Weight ]:
298.38100

[ Exact Mass ]:
298.20000

[ PSA ]:
88.52000

[ LogP ]:
2.80166

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 2-Methyl-2-propanyl {(2S)-1-azido-3-[(3R)-tetrahydro-2H-pyran-3-y l]-2-propanyl}carbamate
  • methyl iodide
  • 1-Boc-D-Pyroglutamic acid ethyl ester
  • (2S,4R)-1-TERT-BUTYL 2-ETHYL 4-ALLYL-5-OXOPYRROLIDINE-1,2-DICARBOXYLATE

DownStream

  • VTP 27999 trifluoroacetate
  • TERT-BUTYL ((S)-1-AMINO-3-((R)-TETRAHYDRO-2H-PYRAN-3-YL)PROPAN-2-YL)(METHYL)CARBAMATE