Tamibarotene

Suppliers

Names

[ Name ]:
Tamibarotene

[Synonym ]:
4-[(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-2-naphthalenyl)carbamoyl]benzoic acid
4-[(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)carbamoyl]benzoic acid
4-((5,5,8,8-Tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)carbamoyl)benzoic acid
4-[(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)carbamoyl]benzoic acid
tamibarotene
Benzoic acid, 4-[[(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)amino]carbonyl]-

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
449.6±45.0 °C at 760 mmHg

[ Melting Point ]:
231-232ºC

[ Molecular Formula ]:
C₂₂H₂₅NO₃

[ Molecular Weight ]:
351.439

[ Flash Point ]:
225.7±28.7 °C

[ Exact Mass ]:
351.183441

[ PSA ]:
66.40000

[ LogP ]:
6.48

[ Vapour Pressure ]:
0.0±1.2 mmHg at 25°C

[ Index of Refraction ]:
1.593

MSDS

Click to get detail MSDS

Safety Information

[ Hazard Codes ]:
Xi

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2924299090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

METHYL4-((5,5,8,8-TETRAMETHYL-5,6,7,8-TETRAHYDRONAPHTHALEN-2-YL)CARBAMOYL)BENZOATE
2,5-Dimethyl-2,5-hexanediol
2,5-Dichloro-2,5-dimethylhexane
1,1,4,4-Tetramethyl-1,2,3,4-tetrahydronaphthalene
2-Nitro-5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalene
5,5,8,8-Tetramethyl-5,6,7,8-tetrahydronaphthalen-2-ylamine

DownStream

Customs

[ HS Code ]: 2924299090

[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

Retinoic acid acts as a selective human IgA switch factor.

Hum. Immunol. 75(8) , 923-9, (2014)

Retinoic acid (RA) is known to have several functions that lead to a potent mucosal IgA response. Nevertheless, its exact role in human IgA synthesis has yet to be elucidated. Thus, we investigated th...

Retinoid signaling is necessary for, and promotes long-term memory formation following operant conditioning.

Neurobiol. Learn. Mem. 114 , 127-40, (2014)

Retinoic acid, a metabolite of vitamin A, is proposed to play an important role in vertebrate learning and memory, as well as hippocampal-dependent synaptic plasticity. However, it has not yet been de...

Role of hematopoietic stem cell transplantation for relapsed acute promyelocytic leukemia: a retrospective analysis of JALSG-APL97.

Cancer Sci. 104(10) , 1339-45, (2013)

For patients with relapsed acute promyelocytic leukemia (APL), all-trans retinoic acid-based salvage regimens can achieve second complete remission (CR2), but the optimal post-remission strategy for A...

Keto Tamibarotene
N-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)acetamide(Tamibarotene)
{[2-(Bromomethyl)oxolan-2-yl]methyl}trimethylsilane
tert-butyl (2S)-2-[[3-(4-bromo-2-nitrophenyl)oxetan-3-yl]carbamoyl]pyrrolidine-1-carboxylate
tert-butyl (2S)-2-[[3-(2-amino-4-bromophenyl)oxetan-3-yl]carbamoyl]pyrrolidine-1-carboxylate
Methyl 6-cyano-2-(trifluoromethyl)nicotinate
tert-Butyl (3R,4R)-3-acetyl-4-methylpyrrolidine-1-carboxylate
1-(Cyclobutylmethyl)-4-methoxy-2-oxopyridine-3-carbonitrile
1-(Cyclobutylmethyl)-4-hydroxy-2-oxopyridine-3-carbonitrile
benzyl 3-hydroxy-1-(2-(2-methyl-5-(4-(methylsulfonyl)phenyl)-1-phenyl-1H-pyrrol-3-yl)ethylamino)-1-oxopropan-2-ylcarbamate
1-allyl-6-(2-chloro-5-methylpyrimidin-4-yl)-1H-indole
3-bromo-6-(2-naphthalenyl)-9-phenyl-9H-Carbazole

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.