(R,E)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide

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Names

[ Name ]:
(R,E)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide

[Synonym ]:
2-Butenamide, N-[4-[(3-chloro-4-fluorophenyl)amino]-7-[[(3R)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-, (2E)-
(2E)-N-{4-[(3-Chloro-4-fluorophenyl)amino]-7-[(3R)-tetrahydro-3-furanyloxy]-6-quinazolinyl}-4-(dimethylamino)-2-butenamide
(2E)-N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[[(3R)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-2-butenamide
Afatinib Impurity 3

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
676.9±55.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂₄H₂₅ClFN₅O₃

[ Molecular Weight ]:
485.938

[ Flash Point ]:
363.2±31.5 °C

[ Exact Mass ]:
485.162994

[ LogP ]:
3.59

[ Vapour Pressure ]:
0.0±2.1 mmHg at 25°C

[ Index of Refraction ]:
1.668

[ Water Solubility ]:
Insuluble (7.3E-5 g/L) (25 ºC)

Related Compounds

1-(2-Bromopropyl)-3-(methoxymethyl)benzene
4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
5-(3-tert-butyl-1-methyl-1H-pyrazol-4-yl)-1H-imidazol-2-amine
2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
4-(2-Methylpyridin-3-yl)oxolan-3-ol
1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
(4-Methyl-tetrahydro-furan-2-yl)-methanol
N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
(5-((Methylamino)methyl)-1,3,4-thiadiazol-2-yl)methanol dihydrochloride