1-(2-chloro-4-nitrophenyl)-3-[[2-[5-(3,4-dimethoxyphenyl)tetrazol-2-yl]acetyl]amino]thiourea

Names

[ Name ]:
1-(2-chloro-4-nitrophenyl)-3-[[2-[5-(3,4-dimethoxyphenyl)tetrazol-2-yl]acetyl]amino]thiourea

[Synonym ]:
4-(2-Chloro-4-nitrophenyl)-1-(5-(3,4-dimethoxyphenyl)tetrazol-2-yl-acetyl)thiosemicarbazide
2H-Tetrazole-2-acetic acid,5-(3,4-dimethoxyphenyl)-,2-(((2-chloro-4-nitrophenyl)amino)thioxomethyl)hydrazide

Chemical & Physical Properties

[ Density]:
1.6g/cm3

[ Molecular Formula ]:
C₁₈H₁₇ClN₈O₅S

[ Molecular Weight ]:
492.89600

[ Exact Mass ]:
492.07300

[ PSA ]:
203.66000

[ LogP ]:
3.91160

[ Index of Refraction ]:
1.716

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: XF7463610

CHEMICAL NAME :: 2H-Tetrazole-2-acetic acid, 5-(3,4-dimethoxyphenyl)-, 2-(((2-chloro-4-nitrophenyl)amino) thioxomethyl)hydrazide

CAS REGISTRY NUMBER :: 94772-01-7

LAST UPDATED :: 199612

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C18-H17-Cl-N8-O5-S

MOLECULAR WEIGHT :: 492.94

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: IJSBDB Indian Journal of Chemistry, Section B: Organic Chemistry, Including Medicinal Chemistry. (Publications & Information Directorate, Council of Scientific and Industrial Research (CSIR), Hillside Rd., New Delhi 110 012, India) V.14B- 1976- Volume(issue)/page/year: 23,1133,1984

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >1 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PHMGBN Pharmacology: International Journal of Experimental and Clinical Pharmacology. (S. Karger AG, Postfach CH-4009 Basel, Switzerland) V.1- 1968- Volume(issue)/page/year: 35,333,1987

Synthetic Route

Click to get detail synthetic route

Related Compounds

1-(1-Bromopropan-2-yl)-2-(trifluoromethyl)benzene
Phenylmethyl 1-chloro-2,3,4,6,7,8-hexahydro-3,4-dioxopyrrolo[1,2-a]pyrazine-6-carboxylate
1-(4-Fluorophenyl)hexan-2-amine
1-(3-Methoxyphenyl)hexan-2-amine
1-(2-Methoxyphenyl)hexan-2-amine
[2-(2-Methylpropyl)pyrazol-3-yl]methanamine
rel-(3R,4S)-7-Fluoro-1,2,3,4-tetrahydro-6-(1H-indol-7-yl)-2,2,4,8-tetramethyl-3-quinolinol
5-(5-Bromo-2-chlorophenyl)-1,2,4-oxadiazole-3-carboxylic acid
5-(4-Bromo-2-methylphenyl)-1,2,4-oxadiazole-3-carboxylic acid
4-(1-Methyl-1h-indol-3-yl)butan-1-amine

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