HBTU

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Names

[ CAS No. ]:
94790-37-1

[ Name ]:
HBTU

[Synonym ]:
N-[(1H-1,2,3-Benzotriazol-1-yloxy)(dimethylamino)methylene]-N-methylmethanaminium hexafluorophosphate
T56 BNNNJ BOYN1&1&UK1&1 &&PF6- salt
Methanaminium, N-[(1H-1,2,3-benzotriazol-1-yloxy)(dimethylamino)methylene]-N-methyl-, hexafluorophosphate
N,N,N′,N′-Tetramethyl-O-(1H-benzotriazol-1-yl)uronium hexafluorophosphate
MFCD00075445
O-(Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate
N-[(1H-Benzotriazol-1-yloxy)(dimethylamino)methylene]-N-methylmethanaminium hexafluorophosphate
(1H-Benzotriazol-1-yloxy)(dimethylamino)-N,N-dimethylmethaniminium hexafluorophosphate
[benzotriazol-1-yloxy(dimethylamino)methylidene]-dimethylazanium,hexafluorophosphate
EINECS 423-020-5
HBTU
O-(Benzotriazol-1-yl)-N,N,N′,N′-tetramethyluronium hexafluorophosphate
T56 BNNNJ BOYN1&1&UK1&1 &&PF6-
N-[(1H-benzotriazol-1-yloxy)(dimethylamino)methylidene]-N-methylmethanaminium hexafluorophosphate
O-Benzotriazol-1-yl-N,N,N',N'-tetramethyluronium hexafluorophosphate

Chemical & Physical Properties

[ Melting Point ]:
200 °C (dec.)(lit.)

[ Molecular Formula ]:
C11H16F6N5OP

[ Molecular Weight ]:
379.24200

[ Flash Point ]:
200°C

[ Exact Mass ]:
379.10000

[ PSA ]:
59.78000

[ LogP ]:
3.43200

[ Storage condition ]:
2-8°C

[ Water Solubility ]:
acetonitrile: 0.1 g/mL, clear

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07, GHS08

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H315-H317-H319-H334-H335

[ Precautionary Statements ]:
P261-P280-P284-P304 + P340-P305 + P351 + P338-P342 + P311

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn:Harmful

[ Risk Phrases ]:
R20/21/22;R36/37/38

[ Safety Phrases ]:
S26-S36/37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
29339980

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Tetramethylurea
  • 1-Hydroxy-1,2,3-benzotriazole potassium salt

DownStream

  • 1-Hydroxybenzotriazole
  • Tetramethylurea
  • 9-methoxy-2,3-dimethyl-9-phenyl-7H-8,9-dihydropyrano[2,3-c]imidazo[1,2-a]pyridine-6-carboxylic acid methylamide
  • IRAK-4 protein kinase inhibitor 2
  • 1H-Indole-2-carboxylic acid methoxy-methyl-amide
  • 1,1,3,3-tetramethyl-2-(4-methylphenyl)sulfonyl-guanidine

Articles

Quantification of plasma HIV RNA using chemically engineered peptide nucleic acids.

Nat. Commun. 5 , 5079, (2014)

The remarkable stability of peptide nucleic acids (PNAs) towards enzymatic degradation makes this class of molecules ideal to develop as part of a diagnostic device. Here we report the development of ...

Polyamidoamine (PAMAM) dendrimers modified with short oligopeptides for early endosomal escape and enhanced gene delivery.

Int. J. Pharm. 492 , 233-43, (2015)

Recently, non-viral vectors have become a popular research topic in the field of gene therapy. In this study, we conjugated short oligopeptides to polyamidoamine-generation 4 (PAMAM G4) to achieve hig...

The uptake of trehalose glycolipids by macrophages is independent of Mincle.

ChemBioChem. 16(4) , 683-93, (2015)

Trehalose glycolipids play an important role in the pathogenesis of Mycobacterium tuberculosis and are used as adjuvants for vaccines; however, much still remains unanswered about the mechanisms throu...


More Articles

Related Compounds

  • 4-[2-Ethoxy-5-(1-piperazinylsulfonyl)benzoamido]-1-methyl-3-propyl-1H-pyrazole-5-carboxamide
  • tert-butyl 3-acetyl-5H,6H,7H,8H-imidazo[1,2-a]pyrimidine-8-carboxylate
  • 4-acetyl-7-tert-butyl-4H,5H,6H,7H-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid
  • 3-{4-acetyl-5,7-dimethyl-4H,5H,6H,7H-pyrazolo[1,5-a]pyrimidin-6-yl}propanoic acid
  • rac-(1R,2S)-2-{[(tert-butoxy)carbonyl]amino}cyclopentane-1-sulfonic acid
  • tert-butyl N-(2-fluoro-1,2,3,4-tetrahydronaphthalen-1-yl)carbamate
  • tert-butyl N-[(4-fluorophenyl)methyl]-N-(prop-2-en-1-yl)carbamate
  • rac-tert-butyl (3R,4R)-3-fluoro-4-phenylpyrrolidine-1-carboxylate
  • tert-butyl N-[(2-fluorophenyl)methyl]-N-(prop-2-en-1-yl)carbamate
  • 3-Acetyl-2-benzyl-1,3-thiazolidine-4-carboxylic acid
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