Spirapril hydrochloride

Suppliers

Names

[ CAS No. ]:
94841-17-5

[ Name ]:
Spirapril hydrochloride

[Synonym ]:
TI 211-950
Sandopril
(8S-(7(R*(R*)),8R*))-7-(2-((1-(ethoxycarbonyl)-3-phenylpropyl)amino)-1-oxopropyl)-1,4-Dithia-7-azaspiro[4.4]nonane-8-carboxylic acid monohydrochloride
(8S)-7-[(2S)-2-{[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}propanoyl]-1,4-dithia-7-azaspiro[4.4]nonane-8-carboxylic acid hydrochloride (1:1) (non-preferred name)
Renormax
Spirapril HCl
spiprapril hydrochloride
(8S)-7-[(2S)-2-{[(2S)-1-Ethoxy-1-oxo-4-phenyl-2-butanyl]amino}propanoyl]-1,4-dithia-7-azaspiro[4.4]nonane-8-carboxylic acid hydrochloride (1:1)
(8S)-7((S)-N-((S)-1-Carboxy-3-phenylpropyl)alanyl)-1,4-dithia-7-azaspiro[4.4]nonane-8-carboxylic acid 1-ethyl ester monohydrochloride
spirapril hydrochloride

Chemical & Physical Properties

[ Boiling Point ]:
697.8ºC at 760mmHg

[ Melting Point ]:
192-194ºC (dec.)

[ Molecular Formula ]:
C22H31ClN2O5S2

[ Molecular Weight ]:
503.07500

[ Flash Point ]:
375.8ºC

[ Exact Mass ]:
502.13600

[ PSA ]:
146.54000

[ LogP ]:
3.52160

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Spirapril
  • N-[(S)-1-Ethoxycarbonyl-3-phenylpropyl]-L-alanine
  • (8S)-1,4-dithia-7-azaspiro[4.4]nonane-8-carboxylic acid
  • N-Cbz-4-keto-L-proline ethyl ester
  • N-[(phenylmethoxy)carbonyl]-1,4-dithia-7-azaspiro[4.4]nonane-8(S)-carboxylic acid ethyl ester
  • N-Carbobenzoxy-4-oxo-L-proline

DownStream

Related Compounds

  • Spirapril hydrochloride
  • Spirapril hydrochloride monohydrate
  • Tyrocidine, hydrochloride
  • Triprolidine hydrochloride
  • Minoxidil hydrochloride
  • neomycin hydrochloride
  • 3-Methyl-9-oxa-2-thia-12-azadispiro[4.0.5^{6}.3^{5}]tetradecan-13-one
  • 4-(1,2-Dimethylcyclopropyl)-8-oxa-1-azaspiro[4.5]decan-2-one
  • 2-Cyclobutanecarbonyl-4-ethyl-1,3-thiazol-5-amine
  • 1-{2-[Bromo(2-methylcyclopropyl)methyl]-1,3-thiazol-5-yl}ethan-1-one
  • 4-[1-(5-Methyl-1,3-thiazol-2-yl)pyrrolidine-3-carbonyl]morpholine
  • 1'-(3-Methylbutyl)-4-azaspiro[bicyclo[2.2.2]octane-2,2'-pyrrolidine]
  • 8-Cyclopropyl-3,3-dimethyl-2,6-dioxa-10-azaspiro[4.5]decane
  • 8-(Methoxymethyl)-2,2-dimethyl-5-oxa-9-azaspiro[3.5]nonane
  • 2,2-Dimethyl-1,9-dioxa-5-azaspiro[5.6]dodecane
  • 7,7-Diethyl-2,2-bis(fluoromethyl)-5-oxa-9-azaspiro[3.5]nonane
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