Spirapril hydrochloride

Suppliers

Names

[ CAS No. ]:
94841-17-5

[ Name ]:
Spirapril hydrochloride

[Synonym ]:
TI 211-950
Sandopril
(8S-(7(R*(R*)),8R*))-7-(2-((1-(ethoxycarbonyl)-3-phenylpropyl)amino)-1-oxopropyl)-1,4-Dithia-7-azaspiro[4.4]nonane-8-carboxylic acid monohydrochloride
(8S)-7-[(2S)-2-{[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}propanoyl]-1,4-dithia-7-azaspiro[4.4]nonane-8-carboxylic acid hydrochloride (1:1) (non-preferred name)
Renormax
Spirapril HCl
spiprapril hydrochloride
(8S)-7-[(2S)-2-{[(2S)-1-Ethoxy-1-oxo-4-phenyl-2-butanyl]amino}propanoyl]-1,4-dithia-7-azaspiro[4.4]nonane-8-carboxylic acid hydrochloride (1:1)
(8S)-7((S)-N-((S)-1-Carboxy-3-phenylpropyl)alanyl)-1,4-dithia-7-azaspiro[4.4]nonane-8-carboxylic acid 1-ethyl ester monohydrochloride
spirapril hydrochloride

Chemical & Physical Properties

[ Boiling Point ]:
697.8ºC at 760mmHg

[ Melting Point ]:
192-194ºC (dec.)

[ Molecular Formula ]:
C22H31ClN2O5S2

[ Molecular Weight ]:
503.07500

[ Flash Point ]:
375.8ºC

[ Exact Mass ]:
502.13600

[ PSA ]:
146.54000

[ LogP ]:
3.52160

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Spirapril
  • N-[(S)-1-Ethoxycarbonyl-3-phenylpropyl]-L-alanine
  • (8S)-1,4-dithia-7-azaspiro[4.4]nonane-8-carboxylic acid
  • N-Cbz-4-keto-L-proline ethyl ester
  • N-[(phenylmethoxy)carbonyl]-1,4-dithia-7-azaspiro[4.4]nonane-8(S)-carboxylic acid ethyl ester
  • N-Carbobenzoxy-4-oxo-L-proline

DownStream

Related Compounds

  • Spirapril hydrochloride
  • Spirapril hydrochloride monohydrate
  • Tyrocidine, hydrochloride
  • Triprolidine hydrochloride
  • Minoxidil hydrochloride
  • neomycin hydrochloride
  • 4-(1-Bromopropyl)-1,2-dichlorobenzene
  • 5-(2-Phenylethenyl)-1,3-oxazolidin-2-one
  • (2-Oxocyclobutyl)methyl acetate
  • Methyl 2-oxo-3-(3,4,5-trimethoxyphenyl)propanoate
  • (Phe(4Br)12)deacetyl-thymosin beta4
  • Methyl (1R,3R,3AR,6R,6AR)-6-acetyl-3-{[tert-butyl(dimethyl)silyl]oxy}octahydro-1-pentalenecarboxylate
  • Tert-butyl 3-hydroxy-4-methylenepyrrolidine-1-carboxylate
  • 3-(2-Pyrimidinyl)quinoline
  • Ethyl 3-[(pyridin-4-yl)amino]benzoate
  • 2-(2-Chloro-2-fluorocyclopropyl)acetic acid
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