1H-Benzotriazole

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Names

[ CAS No. ]:
95-14-7

[ Name ]:
1H-Benzotriazole

[Synonym ]:
BENZOTRIAZOLE PHOTOGRADE
1H-Benzo[d][1,2,3]triazole
Benzotriazol
HETEROCYLIC NITROGEN
cobratec99
1h-benzo
U-6233
1, 2, 3 BENZOTRIAZOLE
T706
1,2,3-1H-Benzotriazole
Seetec BT
1H-benzo[1,2,3]triazole
Cobratec
MFCD00005699
EINECS 202-394-1
1,2,3-BENZOTRIALOLE ( BTA )
1,2,3-BENZOTRIAZOLE,1H-BENZO[D][1,2,3]TRIAZOLE
1,2,3-Benzotriazole(electronicgrade)
1.2.3-Benzotrialole
1,2,3-Benzotriazole
1,2,3-triazaindene
1,2,3,-BENZOTRIAZOLE
Benzotriazole (BTA)
BTA
T56 BMNNJ
1,2,3-Benzotriazole BTA
1,2,3-BENZO TRIAZOLE
RusMin R
1H-BENZOTRIAZOLE FOR SYNTHESIS
1H-1,2,3-Benzotriazole
1H-Benzotriazole
1,2,3-triaza-1H-indene
1,2,3 BENZOTRIAZOLE (BTA)
1,2,3-BENZOTRIAZOL ZUR SYNTHESE
1H-BENZOTRIAZOLE (BTA)
Benzotriazole
BLS 1326
1,2,3-Benzotriazole(BTA)

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
204 ºC (15 mmHg)

[ Melting Point ]:
97-99 °C(lit.)

[ Molecular Formula ]:
C6H5N3

[ Molecular Weight ]:
119.12

[ Flash Point ]:
170 ºC

[ Exact Mass ]:
119.048347

[ PSA ]:
41.57000

[ LogP ]:
1.34

[ Vapour density ]:
4.1 (vs air)

[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C

[ Index of Refraction ]:
1.715

[ Stability ]:
Stable, but may be light sensitive. Incompatible with strong oxidizing agents, heavy metals.

[ Water Solubility ]:
25 g/l in water (20 ºC)

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DM1225000
CHEMICAL NAME :
1H-Benzotriazole
CAS REGISTRY NUMBER :
95-14-7
BEILSTEIN REFERENCE NO. :
0112133
LAST UPDATED :
199710
DATA ITEMS CITED :
21
MOLECULAR FORMULA :
C6-H5-N3
MOLECULAR WEIGHT :
119.14
WISWESSER LINE NOTATION :
T56 BMNNJ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
560 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1910 mg/m3/3H
TOXIC EFFECTS :
Lungs, Thorax, or Respiration - structural or functional change in trachea or bronchi Lungs, Thorax, or Respiration - dyspnea Lungs, Thorax, or Respiration - other changes
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
615 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
400 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
238 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
450 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
500 mg/kg
TOXIC EFFECTS :
Autonomic Nervous System - other (direct) parasympathomimetic Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - cyanosis
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
109 mg/kg/26W-I
TOXIC EFFECTS :
Endocrine - other changes Blood - normocytic anemia Blood - leukopenia
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
220 gm/kg/78W-I
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Brain and Coverings - tumors
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
770 gm/kg/78W-I
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Lungs, Thorax, or Respiration - tumors Lungs, Thorax, or Respiration - bronchiogenic carcinoma

MUTATION DATA

TYPE OF TEST :
Morphological transformation
TEST SYSTEM :
Rodent - rat Embryo
DOSE/DURATION :
94 ug/plate
REFERENCE :
JJATDK JAT, Journal of Applied Toxicology. (John Wiley & Sons Ltd., Baffins Lane, Chichester, W. Sussex PO19 1UD, UK) V.1- 1981- Volume(issue)/page/year: 1,190,1981 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-RUSSIA:STEL 5 mg/m3;Skin JAN 1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 82113 No. of Facilities: 1661 (estimated) No. of Industries: 23 No. of Occupations: 33 No. of Employees: 5550 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 82113 No. of Facilities: 17143 (estimated) No. of Industries: 144 No. of Occupations: 107 No. of Employees: 279549 (estimated) No. of Female Employees: 40869 (estimated)

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302 + H332-H319-H412

[ Precautionary Statements ]:
P273-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
F:Flammable

[ Risk Phrases ]:
R11;R20/21/22;R36/37/38;R5

[ Safety Phrases ]:
S26-S36/37-S61-S45-S36/37/39-S28A

[ RIDADR ]:
2811

[ WGK Germany ]:
1

[ RTECS ]:
DM1225000

[ HS Code ]:
2933990090

Synthetic Route

Precursor & DownStream

Precursor

  • o-Phenylenediamine
  • benzo-1,2,3,4-tetrazine 1,3-dioxide
  • Benzyl 1H-benzotriazole-1-carboxylate
  • benzotriazol-1-yl-(4-chlorophenyl)methanone
  • 1H-1,2,3-benzotriazol-1-yl(4-bromophenyl)methanone
  • 1H-1,2,3-benzotriazol-1-yl(4-iodophenyl)methanone
  • 1-(tert-Butoxycarbonyl)benzotriazole
  • 1,2-Dinitrobenzene

DownStream

  • 1-[(4-Methylphenyl)sulfonyl]-1H-benzotriazole
  • Fmoc-leu-bt
  • 1-(Phenoxymethyl)-1H-benzotriazole
  • N-(benzotriazol-1-ylmethyl)benzamide
  • 1,2,3-triazole-4,5-dicarboxylic acid
  • benzotriazol-1-yl-acetic acid
  • 2-(2H-BENZO[D][1,2,3]TRIAZOL-2-YL)ACETIC ACID
  • 1-methylsulfonylbenzotriazole
  • n-methylbenzol-1,2-diamin
  • 1-(PROP-2-YN-1-YL)-1H-BENZO[D][1,2,3]TRIAZOLE

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

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Environ. Sci. Pollut. Res. Int. 22(8) , 5842-9, (2015)

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Environ. Sci. Pollut. Res. Int. 22(2) , 1095-112, (2015)

A multi-residue method, based on gas chromatography coupled to tandem mass spectrometry (GC-MS/MS), has been developed for the determination of 70 organic micropollutants from various chemical classes...


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Related Compounds

  • 1H-Benzotriazole
  • N-Cbz-1H-benzotriazole
  • 1-TMS-1H-benzotriazole
  • 5-IODO-1H-BENZOTRIAZOLE
  • N-Fmoc-1H-benzotriazole
  • 1-iodo-1H-benzotriazole
  • 2-Methyl-3-(2,4,5-trifluorophenyl)propanoic acid
  • 5-Methoxy-4-nitropicolinic Acid
  • 2-Isobutyl-3H-imidazo[4,5-b]pyridine-5-carboxylic acid
  • Ethyl 7-bromo-4-chloropyrrolo[2,1-f][1,2,4]triazine-5-carboxylate
  • 2-Amino-5-(4-ethylpiperazin-1-yl)-N-methylbenzamide
  • 2-Amino-N-ethyl-5-(4-methylpiperazin-1-yl)benzamide
  • 2-Chloro-4-methoxy-6-phenylpyridine
  • Piperazine, 3,3,5-trimethyl-1-[4-(1-methylethoxy)phenyl]-
  • 2-Bromo-4-chloro-6-fluoro-N-hydroxybenzimidamide
  • 2-Oxobutanethioamide
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