2-methylbenzoxazole

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Names

[ CAS No. ]:
95-21-6

[ Name ]:
2-methylbenzoxazole

[Synonym ]:
2-Methylbenzoxazole
usafek-982
2-Methylbenzoxazoic
2-Methyl-benzooxazole
2-Methylbenzoxazol
EINECS 202-399-9
Benzoxazole,2-methyl
MFCD00005771
2-methyl benzoxazole
METHYLBENZOXAZOLE
2-methyl-1,3-benzoxazole
2-METHYLBENZODOXAZOLE
TABAXOL

Chemical & Physical Properties

[ Density]:
1.121 g/mL at 25 °C(lit.)

[ Boiling Point ]:
178 °C(lit.)

[ Melting Point ]:
5-10 °C(lit.)

[ Molecular Formula ]:
C8H7NO

[ Molecular Weight ]:
133.14700

[ Flash Point ]:
167 °F

[ Exact Mass ]:
133.05300

[ PSA ]:
26.03000

[ LogP ]:
2.13620

[ Index of Refraction ]:
n20/D 1.548(lit.)

[ Storage condition ]:
Refrigerator

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DM4850000
CHEMICAL NAME :
Benzoxazole, 2-methyl-
CAS REGISTRY NUMBER :
95-21-6
LAST UPDATED :
199701
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C8-H7-N-O
MOLECULAR WEIGHT :
133.16
WISWESSER LINE NOTATION :
T56 BN DOJ C1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,890,1986
TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration into the eye
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,890,1986 ** ACUTE TOXICITY DATA **
TYPE OF TEST :
LD40 - Lethal Dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1100 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JACSAT Journal of the American Chemical Society. (American Chemical Soc., Distribution Office Dept. 223, POB 57136, West End Stn., Washington, DC 20037) V.1- 1879- Volume(issue)/page/year: 67,905,1945
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
400 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: AD277-689

Safety Information

[ Symbol ]:

GHS05, GHS07

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H302-H315-H318-H335

[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xn:Harmful;

[ Risk Phrases ]:
R22;R36/37/38

[ Safety Phrases ]:
S26-S36/37/39-S37/39

[ RIDADR ]:
UN 1760

[ WGK Germany ]:
3

[ RTECS ]:
DM4850000

[ Packaging Group ]:
III

[ Hazard Class ]:
8

[ HS Code ]:
29349990

Synthetic Route

Precursor & DownStream

Precursor

  • acetoaminophenol
  • Ortho-Hydroxyacetophenone
  • 1-(2-HYDROXYPHENYL)ETHAN-1-ONE OXIME
  • 2'-bromoacetanilide
  • Acetamide,N-(2-iodophenyl)-
  • 1,3-DECADIYNE
  • aminophenol
  • Triethyl orthoacetate
  • 6-(1-aminoethylidene)cyclohexa-2,4-dien-1-one
  • 2-NITROPHENYL ACETATE

DownStream

  • 2-Methyl-6-nitrobenzoxazole
  • 2-METHYL-5-NITROBENZO[D]OXAZOLE
  • 2-(2-benzoxazolyl)malondialdehyde
  • 2-(diethoxyphosphorylmethyl)-1,3-benzoxazole
  • aminophenol
  • 2-(nitromethyl)-1,3-benzoxazole
  • ACETAMIDE, N-(2-HYDROXY-4-NITROPHENYL)-
  • 4-(2-Benzooxazol-2-ylethenyl)-N,N-dimethylaniline
  • 2-(tribromomethyl)-1,3-benzoxazole
  • 2-Amino-4-nitrophenol

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Gerard Mosciano

Perfum. Flavor. 34 (1) , 58-59, (2009)


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Related Compounds

  • 4-Amino-2-methylbenzoxazole
  • 7-bromo-2-methylbenzoxazole
  • 6-Bromo-2-methylbenzoxazole
  • 6-Ethoxy-2-methylbenzoxazole
  • 5-Chloro-2-methylbenzoxazole
  • 5-Fluoro-2-Methylbenzoxazole
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine
  • 4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide
  • N-[3-(Aminooxy)propyl]-N-butyl-1-butanamine