2-Chloroaniline
Suppliers
Names
[ CAS No. ]:
95-51-2
[ Name ]:
2-Chloroaniline
[Synonym ]:
Benzenamine, 2-chloro-
1-Chloro-2-aminobenzene
2-chlorophenylamine
2-chloro-aniline
2-Chloroanline
OCA
O-CHLOROANILINE D
2-CHLOROBENZAMINE
BENZENAMINE,2-CHLORO-
MFCD00007656
2-Chlorobenzenamine
ortho-chloroaniline
EINECS 202-426-4
2-CHLORO ANILINE
o-Chloraniline
ZR BG
1-Amino-2-chlorobenzene
2-Aminochlorobenzene
2-CHLOROANILINE FOR SYNTHESIS
o-chloro-anilin
o-Chloroaniline
2-CHLORANILIN
2-CHLOROANALINE
Chemical & Physical Properties
[ Density]:
1.2±0.1 g/cm3
[ Boiling Point ]:
208.8±0.0 °C at 760 mmHg
[ Melting Point ]:
0-3 °C
[ Molecular Formula ]:
C6H6ClN
[ Molecular Weight ]:
127.572
[ Flash Point ]:
97.8±0.0 °C
[ Exact Mass ]:
127.018875
[ PSA ]:
26.02000
[ LogP ]:
1.91
[ Vapour Pressure ]:
0.2±0.4 mmHg at 25°C
[ Index of Refraction ]:
1.598
[ Water Solubility ]:
5.13 g/L (20 ºC)
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- BX0525000
- CHEMICAL NAME :
- Aniline, o-chloro-
- CAS REGISTRY NUMBER :
- 95-51-2
- LAST UPDATED :
- 199712
- DATA ITEMS CITED :
- 18
- MOLECULAR FORMULA :
- C6-H6-Cl-N
- MOLECULAR WEIGHT :
- 127.58
- WISWESSER LINE NOTATION :
- ZR BG
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 256 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Mammal - cat
- DOSE/DURATION :
- 222 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Mammal - cat
- DOSE/DURATION :
- 310 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - respiratory depression Nutritional and Gross Metabolic - body temperature decrease
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 14560 mg/kg/13W-I
- TOXIC EFFECTS :
- Endocrine - changes in spleen weight Blood - pigmented or nucleated red blood cells Blood - methemoglobinemia-carboxyhemoglobin
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 14560 mg/kg/13W-I
- TOXIC EFFECTS :
- Endocrine - changes in spleen weight Blood - pigmented or nucleated red blood cells Blood - methemoglobinemia-carboxyhemoglobin
MUTATION DATA
- TYPE OF TEST :
- Mutation in mammalian somatic cells
- TEST SYSTEM :
- Rodent - hamster Lung
- DOSE/DURATION :
- 600 ug/L
- REFERENCE :
- BLFSBY Basic Life Sciences. (Plenum Pub. Corp., 223 Spring St., New York, NY 10003) V.1- 1973- Volume(issue)/page/year: 39,359,1986 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83962 No. of Facilities: 38 (estimated) No. of Industries: 2 No. of Occupations: 3 No. of Employees: 18138 (estimated)
Safety Information
[ Symbol ]:
GHS06, GHS08, GHS09
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H301 + H311 + H331-H319-H373-H410
[ Precautionary Statements ]:
P261-P273-P280-P301 + P310 + P330-P403 + P233
[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ Hazard Codes ]:
T:Toxic;N:Dangerousfortheenvironment;
[ Risk Phrases ]:
R23/24/25;R33;R50/53
[ Safety Phrases ]:
S28-S36/37-S45-S60-S61-S28A
[ RIDADR ]:
UN 2019 6.1/PG 2
[ WGK Germany ]:
2
[ RTECS ]:
BX0525000
[ Packaging Group ]:
II
[ Hazard Class ]:
6.1
[ HS Code ]:
2921420090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2921420090
[ Summary ]:
HS:2921420090 aniline derivatives and their salts VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%
Articles
J. Chromatogr. A. 1356 , 221-9, (2014)
For the expanded application area, fast trace analysis of certain high boiling point (i.e., 150-250 °C) volatile organic compounds (HVOCs) in water, a large volume-direct aqueous injection-gas chromat...
J. Hazard. Mater. 179(1-3) , 875-82, (2010)
A new strain Delftia tsuruhatensis H1 able to degrade several chloroanilines (CAs) as individual compounds or a mixture was isolated from a CA-degrading mixed bacterial culture. The isolated strain co...
Biomed. Environ. Sci. 20(2) , 141-5, (2007)
To identify the bacteria tolerating chlorinated anilines and to study the biodegradability of o-chloroaniline and its coexistent compounds.Microbial community of complex bacteria was identified by pla...