3,4-Dimethylaniline

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Names

[ CAS No. ]:
95-64-7

[ Name ]:
3,4-Dimethylaniline

[Synonym ]:
aniline,3,4-dimethyl
3,4-XYLIDINE (3,4-DIMETHYLANILINE)
3,4-DIMETHYLANILIN
3,4-dimethyl aniline
4-AMINO-O-XYLENE
3,4-Xylidine
3,4-DIMETHYLANILINE FOR SYNTHESIS
3,4-dimethylphenylamine
MFCD00007810
3,4-Xylylamine
EINECS 202-437-4
3,4-DIMETHYLANILINE D
3,4-Dimethylbenzenamine
3 4-DIMETHYLANILINE
3,4-DitolueneAmine
3,4-Dimethylaniline
Aniline, 3,4-dimethyl-
ASYM-O-XYLIDINE
3,4-DIMETHYLANILINE/3,4-XYLIDINE
ZR C1 D1
Benzenamine, 3,4-dimethyl-

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
228.0±0.0 °C at 760 mmHg

[ Melting Point ]:
49-51 °C(lit.)

[ Molecular Formula ]:
C8H11N

[ Molecular Weight ]:
121.180

[ Flash Point ]:
98.3±0.0 °C

[ Exact Mass ]:
121.089149

[ PSA ]:
26.02000

[ LogP ]:
1.86

[ Vapour Pressure ]:
0.1±0.4 mmHg at 25°C

[ Index of Refraction ]:
1.559

[ Water Solubility ]:
<1 g/L (24 ºC)

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
ZE9450000
CHEMICAL NAME :
3,4-Xylidine
CAS REGISTRY NUMBER :
95-64-7
BEILSTEIN REFERENCE NO. :
0507414
LAST UPDATED :
199710
DATA ITEMS CITED :
8
MOLECULAR FORMULA :
C8-H11-N
MOLECULAR WEIGHT :
121.20
WISWESSER LINE NOTATION :
ZR C1 D1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
812 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
707 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Bird - wild bird species
DOSE/DURATION :
5600 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TEST SYSTEM :
Rodent - mouse
DOSE/DURATION :
100 mg/kg
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 46,305,1977

Safety Information

[ Symbol ]:

GHS06, GHS08, GHS09

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H301 + H311 + H331-H373-H411

[ Precautionary Statements ]:
P261-P273-P280-P301 + P310-P311

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges

[ Hazard Codes ]:
T:Toxic;N:Dangerousfortheenvironment;

[ Risk Phrases ]:
R23/24/25;R33;R51/53

[ Safety Phrases ]:
S28-S36/37-S45-S61-S28A

[ RIDADR ]:
UN 3452 6.1/PG 2

[ WGK Germany ]:
2

[ RTECS ]:
ZE9450000

[ Packaging Group ]:
II

[ Hazard Class ]:
6.1

[ HS Code ]:
29214910

Synthetic Route

Precursor & DownStream

Precursor

  • 3,4-Dimethylnitrobenzene
  • 4-Iodo-1,2-dimethylbenzene
  • 3,4-Dimethylbromobenzene
  • Methyl fluoride
  • 3-Toluidine
  • 2-(Chloromethyl)-1-methyl-4-nitrobenzene
  • o-xylene
  • N-[1-(3,4-dimethylphenyl)ethylidene]hydroxylamine
  • 3,4-Dimethylacetophenone

DownStream

  • 3,4-dimethyl-N-propan-2-ylaniline
  • 2-CHLORO-N-{[(3,4-DIMETHYLPHENYL)AMINO]CARBONYL}ACETAMIDE
  • Pendimethalin
  • N-(3,4-dimethyl-2,6-dinitrophenyl)-N-pentan-3-ylnitramide
  • 3-chloro-N-(3,4-dimethylphenyl)propanamide
  • 3,4-Dimethyl-N-(pentan-3-yl)aniline
  • 2-amino-4,5-dimethylphenylamine
  • 4-Fluoro-o-xylene
  • 3,4-dimethylphenyl isocyanate

Customs

[ HS Code ]: 2921430090

[ Summary ]:
HS:2921430090 toluidines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Articles

The effect of substituents on the phenyl portion of the imido ligand on the structure and properties of molybdenum(VI) imido complexes.

Inorg. Chem. 41(23) , 5954-60, (2002)

Anilines with alkyl substituents on the phenyl ring (ArNH2 = 2,4,6-trimethylaniline; 2,3-, 2,4-, 2,6-, and 3,4-dimethylaniline; and 2,6-diisopropylaniline) react with MoO(X)2(dtc)2 (X = Cl or Br; dtc ...

Separation and analysis of dimethylaniline isomers by supercritical fluid chromatography—Electrospray ionization tandem mass spectrometry

J. Chromatogr. A. 1216(41) , 6970-3, (2009)

The assessment of human exposure to specific isomers of dimethylanilines (DMA's) is of interest for the evaluation of potential exposure-health outcome relationships. Improved analytical methods will ...

Electron donor-acceptor interaction of 3,4-dimethylaniline with 2,3-dicyano-1,4-naphthoquinone.

Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 78(1) , 480-7, (2011)

The electron donor-acceptor (EDA) interaction between 2,3-dicyano-1,4-naphthoquinone (DCNQ) and 3,4-dimethylaniline (3,4-DMA) is studied in chloroform, dichloromethane and 1:1 (v/v) mixture of chlorof...


More Articles


Related Compounds

  • 3,4-dimethylaniline
  • 6-iodo-3,4-dimethylaniline
  • N-Ethyl-3,4-dimethylaniline
  • N-3-pentyl-3,4-dimethylaniline
  • N-2-propyl-3,4-dimethylaniline
  • 2,6-dibromo-3,4-dimethylaniline
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-chloro-N-[1-(5,6,7,8-tetrahydronaphthalen-2-yl)ethyl]propanamide
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 1,4-dimethyl-N-(7-methylbenzo[1,2-d:4,3-d']bis(thiazole)-2-yl)-1H-pyrazole-5-carboxamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine