1,2,4,5-Tetramethylbenzene

Suppliers

Names

[ CAS No. ]:
95-93-2

[ Name ]:
1,2,4,5-Tetramethylbenzene

[Synonym ]:
Benzene, 1,2,4,5-tetramethyl
Durene
MFCD00008528
EINECS 202-465-7
1,2,4,5-tetramethyl-benzene
Durol

Chemical & Physical Properties

[ Density]:
0.838 g/mL at 25 °C(lit.)

[ Boiling Point ]:
196-197 °C

[ Melting Point ]:
78 °C

[ Molecular Formula ]:
C10H14

[ Molecular Weight ]:
134.21800

[ Flash Point ]:
165 °F

[ Exact Mass ]:
134.11000

[ LogP ]:
2.92020

[ Vapour density ]:
4.6 (vs air)

[ Vapour Pressure ]:
160 mm Hg ( 140 °C)

[ Index of Refraction ]:
1.4790 (81ºC)

[ Water Solubility ]:
insoluble

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DC0500000
CHEMICAL NAME :
Benzene, 1,2,4,5-tetramethyl-
CAS REGISTRY NUMBER :
95-93-2
LAST UPDATED :
199710
DATA ITEMS CITED :
6
MOLECULAR FORMULA :
C10-H14
MOLECULAR WEIGHT :
134.24
WISWESSER LINE NOTATION :
1R B1 D1 E1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
6989 mg/kg
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - lacrimation Lungs, Thorax, or Respiration - dyspnea Blood - hemorrhage
REFERENCE :
DCTODJ Drug and Chemical Toxicology. (Marcel Dekker, 270 Madison Ave., New York, NY 10016) V.1- 1977/78- Volume(issue)/page/year: 1,219,1978
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
180 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#00212 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X2248 No. of Facilities: 242 (estimated) No. of Industries: 3 No. of Occupations: 3 No. of Employees: 2117 (estimated) No. of Female Employees: 1608 (estimated)

Safety Information

[ Symbol ]:

GHS02

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H228

[ Precautionary Statements ]:
P210

[ Hazard Codes ]:
F:Flammable

[ Risk Phrases ]:
R11

[ Safety Phrases ]:
S16

[ RIDADR ]:
UN 1325 4.1/PG 2

[ WGK Germany ]:
1

[ RTECS ]:
DC0500000

[ Packaging Group ]:
III

[ Hazard Class ]:
4.1

[ HS Code ]:
29029080

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • (2,4,5-trimethylphenyl)methanol
  • tetramethylbenzene
  • Acetyl chloride
  • 1,2,3,5-tetramethylbenzene
  • Benzoic acid,2,3,5,6-tetramethyl-
  • Methanol
  • Chloromethane
  • m-Xylene
  • 2,3,5,6-Tetramethyliodobenzene

DownStream

  • Acetamide,N-[(2,4,5-trimethylphenyl)methyl]-
  • 2,4,5-TRIMETHYLBENZYL CHLORIDE
  • chlorodurene
  • 5-(benzo[d][1,3]dioxol-5-yl)pentan-2-one
  • 1,2,3,5-tetramethylbenzene
  • tetramethylbenzene
  • Ethanone,1-(2,3,5,6-tetramethylphenyl)-
  • 1,2,3-Trimethylbenzene
  • Pentamethylbenzene
  • 2,3,5,6-Tetramethylbenzene-1-sulfonyl chloride

Customs

[ HS Code ]: 2902909090

[ Summary ]:
2902909090 other aromatic hydrocarbons。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:2.0%。General tariff:30.0%

Articles

Myofibroblasts from salivary gland adenoid cystic carcinomas promote cancer invasion by expressing MMP2 and CXCL12.

Histopathology 66(6) , 781-90, (2015)

Salivary gland adenoid cystic carcinoma (ACC) is one of the most common malignant tumours in the oral and maxillofacial region, and has high aggressive potential. Tumour and stroma interactions are cr...

Cannabinoid 1 receptors in keratinocytes attenuate fluorescein isothiocyanate-induced mouse atopic-like dermatitis.

Exp. Dermatol. 23(6) , 401-6, (2014)

Atopic dermatitis is a chronic inflammatory disease characterized by an impaired epidermal barrier function combined with a chronic Th2-type inflammatory response and an intense pruritus. Here, we use...

Identification and characterization of D-xylulokinase from the D-xylose-fermenting fungus, Mucor circinelloides.

FEMS Microbiol. Lett. 360(1) , 51-61, (2014)

D-Xylulokinase catalyzes the phosphorylation of D-xylulose in the final step of the pentose catabolic pathway to form d-xylulose-5-phosphate. The D-xylulokinase activity was found to be induced by bot...


More Articles

Related Compounds

  • 1,2,4,5-tetramethylbenzene-d14
  • 13C-1,2,4,5-tetramethylbenzene
  • 1,2,4,5-tetramethylbenzene-3,6-d2
  • 3-iodo-1,2,4,5-tetramethylbenzene
  • 3-bromo-1,2,4,5-tetramethylbenzene
  • 3-Fluoro-1,2,4,5-tetramethylbenzene
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 6-[3-(4,4-Difluoropiperidine-1-carbonyl)piperidin-1-yl]-1,3-dimethyl-1,2,3,4-tetrahydropyrimidine-2,4-dione
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • Ethyl 8-(cyclopropyloxy)-3-formyl-6-quinolinecarboxylate
  • tert-Butyl-DL-alanine