7-METHYL-5,6,7,8-TETRAHYDRO[1]BENZOTHIENO[2,3-D]PYRIMIDIN-4(3H)-ONE

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Names

[ CAS No. ]:
95211-71-5

[ Name ]:
7-METHYL-5,6,7,8-TETRAHYDRO[1]BENZOTHIENO[2,3-D]PYRIMIDIN-4(3H)-ONE

[Synonym ]:
(1)Benzothieno(2,3-d)pyrimidin-4(1H)-one,5,6,7,8-tetrahydro-7-methyl
5,6,7,8-Tetrahydro-7-methyl-(1)benzothieno(2,3-d)pyrimidin-4(1H)-one
7-methyl-3,5,6,7,8-pentahydrobenzo[b]thiopheno[2,3-d]pyrimidin-4-one
7-methyl-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4[3H]one
7-methyl-5,6,7,8-tetrahydrobenzo<b>thieno<2,3-d>pyrimidine-4-one

Chemical & Physical Properties

[ Density]:
1.52g/cm3

[ Boiling Point ]:
477.1ºC at 760 mmHg

[ Molecular Formula ]:
C11H12N2OS

[ Molecular Weight ]:
220.29100

[ Flash Point ]:
242.3ºC

[ Exact Mass ]:
220.06700

[ PSA ]:
73.99000

[ LogP ]:
2.10940

[ Index of Refraction ]:
1.772

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DL8355040
CHEMICAL NAME :
(1)Benzothieno(2,3-d)pyrimidin-4(1H)-one, 5,6,7,8-tetrahydro-7-methyl-
CAS REGISTRY NUMBER :
95211-71-5
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C11-H12-N2-O-S
MOLECULAR WEIGHT :
220.31

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique. (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France) V.9- 1974- Volume(issue)/page/year: 19,420,1984

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Ethyl 2-amino-6-methyl-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate
  • (Z)-Methanimidic acid
  • 2-AMINO-6-METHYL-4,5,6,7-TETRAHYDRO-1-BENZOTHIOPHENE-3-CARBOXAMIDE
  • Triethyl orthoformate
  • 4-Methylcyclohexanone

DownStream

  • 7-METHYL-5,6,7,8-TETRAHYDRO-BENZO[4,5]THIENO[2,3-D]PYRIMIDINE-4-THIOL
  • 4-CHLORO-7-METHYL-5,6,7,8-TETRAHYDRO[1]BENZOTHIENO[2,3-D]PYRIMIDINE

Related Compounds

  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • Ethyl 4-[(3-ethoxy-3-oxo-1-propen-1-yl)oxy]-2-pentynoate
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 2-[3-(Methylsulfanyl)phenyl]ethanimidamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine