GDC-0941

Suppliers

Names

[ Name ]:
GDC-0941

[Synonym ]:
4-(2-(1H-indazol-4-yl)-6-((4-(methylsulfonyl)piperazin-1-yl)methyl)thieno[3,2-d]pyrimidin-4-yl)morpholine
pictrelisib
Thieno[3,2-d]pyrimidine, 2-(1H-indazol-4-yl)-6-[[4-(methylsulfonyl)-1-piperazinyl]methyl]-4-(4-morpholinyl)-
GDC0941
GDC-941
GDC 0941
2-(1H-Indazol-4-yl)-6-{[4-(methylsulfonyl)piperazin-1-yl]methyl}-4-(morpholin-4-yl)thieno[3,2-d]pyrimidin
2-(1H-Indazol-4-yl)-6-{[4-(methylsulfonyl)-1-piperazinyl]methyl}-4-(4-morpholinyl)thieno[3,2-d]pyrimidine
Pictilisib
2-(1H-Indazol-4-yl)-6-[[4-(methylsulfonyl)-1-piperazinyl]methyl]-4-(4-morpholinyl)thieno[3,2-d]pyrimidine
GDC-0941
GDC-0941 bismesylate

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
687.7±65.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂₃H₂₇N₇O₃S₂

[ Molecular Weight ]:
513.636

[ Flash Point ]:
369.7±34.3 °C

[ Exact Mass ]:
513.161682

[ PSA ]:
144.17000

[ LogP ]:
2.04

[ Vapour Pressure ]:
0.0±2.1 mmHg at 25°C

[ Index of Refraction ]:
1.753

Safety Information

[ HS Code ]:
29350090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole
4-(2-CHLORO-6-((4-(METHYLSULFONYL)PIPERAZIN-1-YL)METHYL)THIENO[3,2-D]PYRIMIDIN-4-YL)MORPHOLINE
4-(2-Chlorothieno[3,2-d]pyrimidin-4-yl)morpholine
3-Bromo-2-methylaniline
Bis(pinacolato)diboron
4-Bromoindazole
Thieno[3,2-d]pyrimidine-2,4-diol
Methyl 3-amino-2-thiophenecarboxylate
2,4-Dichlorothieno[3,2-d]pyrimidine
2-Chloro-4-morpholinothieno[3,2-d]pyrimidine-6-carbaldehyde