1-Benzyloxycarbonyl-3-hydroxypiperidine

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Names

[ CAS No. ]:
95798-22-4

[ Name ]:
1-Benzyloxycarbonyl-3-hydroxypiperidine

[Synonym ]:
1-cbz-3-hydroxy-piperidine
N-Cbz-piperidin-3-ol
1-Piperidinecarboxylic acid, 3-hydroxy-, phenylmethyl ester
Benzyl 3-hydroxypiperidine-1-carboxylate
benzyl 3-hydroxytetrahydro-1(2H)-pyridinecarboxylate
N-benzyloxycarbonyl-3-hydroxypiperidine
3-(1-benzyloxycarbonyl)piperidinol
1-N-Cbz-3-hydroxy-piperidine
3-hydroxy-piperidine-1-carboxylic acid benzyl ester
Benzyl 3-hydroxy-1-piperidinecarboxylate
1-benzyloxycarbonylpiperidine-3-ol
Benzyl3-hydroxypiperidine-1-carboxylate
n-cbz-3-hydroxypiperidine
1-Benzyloxycarbonyl-3-hydroxypiperidine

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
384.9±42.0 °C at 760 mmHg

[ Molecular Formula ]:
C13H17NO3

[ Molecular Weight ]:
235.279

[ Flash Point ]:
186.6±27.9 °C

[ Exact Mass ]:
235.120850

[ PSA ]:
49.77000

[ LogP ]:
1.10

[ Vapour Pressure ]:
0.0±0.9 mmHg at 25°C

[ Index of Refraction ]:
1.574

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Safety Information

[ Hazard Codes ]:
Xi

Synthetic Route

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Precursor & DownStream

Precursor

  • piperidin-3-ol hydrochloride
  • Benzyl chloroformate
  • 3-Hydroxypiperidine
  • Phenyl chloroformate
  • Benzyl 5,6-dihydropyridine-1(2H)-carboxylate

DownStream

  • Benzyl 5,6-dihydropyridine-1(2H)-carboxylate
  • (R)-Benzyl 3-hydroxypiperidine-1-carboxylate
  • 1-Cbz-3-piperidinone
  • (3R)-3-Piperidinol

Related Compounds

  • (2S,3S)-2-allyl-1-benzyloxycarbonyl-3-hydroxypiperidine
  • 1-benzyloxycarbonyl-3-butylidene-2,3-dihydro-2-methyl-4-pyridone
  • 1-benzyloxycarbonyl-3-formyl-5-phenyl-7-ethylthiopyrrolo<3,2-d>pyrimidine
  • 1-benzyloxycarbonyl-3-((2,6-dichlorophenyl)hydroxymethyl)-2,3-dihydro-2-methylpyridin-4(1H)-one
  • 1-(benzyloxycarbonyl)-3-(1'-phenyleth-1'-yl)-6,6-dimethylperihydropyrimidin-4-one
  • 1-benzyloxycarbonyl-3-[1-(methylsulfonyloxy)butyl]-2,3-dihydro-2-methyl-4-pyridone
  • 3-{[(Tert-butoxy)carbonyl]amino}-3-cyclopropylhexanoic acid
  • ethyl (3R)-3-amino-3-(1,2-thiazol-5-yl)propanoate
  • O-{[1-(2-bromo-5-methylphenyl)cyclopropyl]methyl}hydroxylamine
  • 2-(6-Chloro-2-methoxypyridin-3-yl)-2-oxoacetic acid
  • 4-(2-Chloro-6-methylpyridin-4-yl)-2-methylbutan-2-amine
  • 1-{1-[2-Chloro-5-(trifluoromethyl)pyridin-3-yl]cyclopropyl}cyclopropan-1-amine
  • 1-[1-(5-Bromo-2-chloropyridin-4-yl)cyclopropyl]ethan-1-one
  • 2-[1-(2-Chloropyridin-3-yl)cyclopropyl]acetic acid
  • 2-[2-Chloro-5-(trifluoromethyl)pyridin-3-yl]-2-methylpropanoic acid
  • 4-Bromo-3-{[(tert-butoxy)carbonyl]amino}-5-fluorobenzoic acid
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