oxolamine
Names
[ CAS No. ]:
959-14-8
[ Name ]:
oxolamine
[Synonym ]:
5-<2-Diaethylamino-aethyl>-3-phenyl-1.2.4-oxadiazol
683-m
diethyl-[2-(3-phenyl-[1,2,4]oxadiazol-5-yl)-ethyl]-amine
1,2,4-Oxadiazole-5-ethanamine, N,N-diethyl-3-phenyl-
3-Phenyl-5-(b-diethylaminoethyl)-1,2,4-oxadiazole
EINECS 213-493-4
AF-438
oxolamine
683 M
5-[2-(diethylamino)ethyl]-3-phenyl-1,2,4-oxadiazole
1,2,4-OXADIAZOLE,5-(2-DIETHYLAMINO)ETHYL)-3-PHENYL
3-Phenyl-5-<2-diaethylamino-aethyl>-1.2.4-oxadiazol
N,N-Diethyl-2-(3-phenyl-1,2,4-oxadiazol-5-yl)ethanamine
oxalamine citrate
MFCD00866857
Chemical & Physical Properties
[ Density]:
1.1±0.1 g/cm3
[ Boiling Point ]:
364.8±44.0 °C at 760 mmHg
[ Molecular Formula ]:
C14H19N3O
[ Molecular Weight ]:
245.320
[ Flash Point ]:
174.4±28.4 °C
[ Exact Mass ]:
245.152817
[ PSA ]:
42.16000
[ LogP ]:
3.50
[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C
[ Index of Refraction ]:
1.531
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- RO0700000
- CHEMICAL NAME :
- 1,2,4-Oxadiazole, 5-(2-(diethylamino)ethyl)-3-phenyl-
- CAS REGISTRY NUMBER :
- 959-14-8
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C14-H19-N3-O
- MOLECULAR WEIGHT :
- 245.36
- WISWESSER LINE NOTATION :
- T5NO DNJ C2N2&2 ER
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >2 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- BCFAAI Bollettino Chimico Farmaceutico. (Societa Editoriale Farmaceutica, Via Ausonio 12, 20123 Milan, Italy) V.33- 1894- Volume(issue)/page/year: 103,115,1964
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 679 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- BCFAAI Bollettino Chimico Farmaceutico. (Societa Editoriale Farmaceutica, Via Ausonio 12, 20123 Milan, Italy) V.33- 1894- Volume(issue)/page/year: 103,115,1964
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 208 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- PMDCAY Progress in Medical Chemistry. (Elsevier Science Pub. Co., Inc., 52 Vanderbilt Ave., New York, NY 10017) V.1- 1961- Volume(issue)/page/year: 3,89,1963
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 672 mg/kg
- TOXIC EFFECTS :
- Behavioral - analgesia Nutritional and Gross Metabolic - body temperature decrease Biochemical - Metabolism (Intermediary) - effect on inflammation or mediation of inflammation
- REFERENCE :
- JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 10,411,1967 *** REVIEWS *** TOXICOLOGY REVIEW ADCSAJ Advances in Chemistry Series. (American Chemical Soc., Distribution Office Dept. 223, POB 57136, West End Stn., Washington, DC 20037) No.1- 1950- Volume(issue)/page/year: 13,271,1970
Safety Information
[ HS Code ]:
2934999090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2934999090
[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%