Endosulfan I

Suppliers

Names

[ CAS No. ]:
959-98-8

[ Name ]:
Endosulfan I

[Synonym ]:
(3α,5aβ,6α,9α,9aβ)-6,7,8,9,10,10-hexachloro-1,5,5a,6,9,9a-hexahydro-6,9-methano-2,4,3-benzodioxathiepin 3-oxide
1,4,5,6,7,7-hexachloro-5-norbornene-2,3-dimethanol cyclic sulfite
6,7,8,9,10,10-hexachloro-1,5,5a,6,9,9a-hexahydro-6,9-methano-2,4,3-benzodioxathiepin-3-oxide
endosulfana
endosulfan1
A-ENDOSULFAN
MFCD00151174
(5aR,6S,9R,9aS)-6,7,8,9,10,10-hexachloro-1,5,5a,6,9,9a-hexahydro-6,9-methano-2,4,3-benzodioxathiepine 3-oxide
Endosulfan I

Chemical & Physical Properties

[ Density]:
1.94

[ Boiling Point ]:
449.7ºC at 760mmHg

[ Melting Point ]:
108 - 110ºC

[ Molecular Formula ]:
C9H6Cl6O3S

[ Molecular Weight ]:
406.92500

[ Flash Point ]:
225.8ºC

[ Exact Mass ]:
403.81700

[ PSA ]:
54.74000

[ LogP ]:
4.55550

[ Index of Refraction ]:
1.674

[ Storage condition ]:
APPROX 4°C

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
RB9275100
CHEMICAL NAME :
5-Norbornene-2,3-dimethanol, 1,4,5,6,7,7-hexachloro-, cyclic sulfite, endo-
CAS REGISTRY NUMBER :
959-98-8
LAST UPDATED :
199710
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C9-H6-Cl6-O3-S

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
76 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: PB85-143766
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Mammal - species unspecified
DOSE/DURATION :
76 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
DEVEAA Defense des Vegetaux. (Federation Nationale des Groupements de Protection des Cultures, 149, rue de Bercy, 75595 Paris Cedex, 12, France) V.1- 1947- Volume(issue)/page/year: 44(262),37,1990 ** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
45 mg/kg/15D-I
TOXIC EFFECTS :
Brain and Coverings - other degenerative changes Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - phosphatases
REFERENCE :
JTEHD6 Journal of Toxicology and Environmental Health. (Hemisphere Pub., 1025 Vermont Ave., NW, Washington, DC 20005) V.1- 1975/76- Volume(issue)/page/year: 28,473,1989

Safety Information

[ Symbol ]:

GHS02, GHS07, GHS08, GHS09

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H225-H304-H315-H336-H361f-H373-H411

[ Precautionary Statements ]:
P210-P260-P280-P301 + P310-P370 + P378-P403 + P235

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges

[ Hazard Codes ]:
T,N,Xn,E

[ Risk Phrases ]:
R24/25

[ Safety Phrases ]:
36/37-45-60-61-62

[ RIDADR ]:
UN 2761

[ RTECS ]:
RB9275100

[ Packaging Group ]:
II

[ Hazard Class ]:
6.1(a)

Synthetic Route

Precursor & DownStream

Precursor

  • 1,2,3,4,7,7-hexachloro-5,6-di(hydroxymethyl)bicyclo[2.2.1]hept-2-ene

DownStream

  • β-Endosulfan
  • 1,3,3A,4,7,7A-Hexahydro-4,5,6,7,8,8-hexachloro-4,7-methanoiso-benzofuran
  • trans-1,4,5,6,7,7-Hexachlor-2,3-bis-hydroxymethyl-bicyclo[2.2.1]hept-5-en
  • ENDOSULFANHYDROXYETHER
  • endosulfan-sulphate
  • THIODAN SULFATE

Related Compounds

  • endosulfan II
  • Endosulfan
  • bis(i-propylamino)bromoborane
  • Eeyarestatin I
  • Etioporphyrin I dihydrobromide
  • silver(I) 2-hydroxyethane-1-thiolate
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • 1-(1-ethyl-2,3-dihydro-1H-indol-5-yl)-3-oxocyclobutane-1-carbonitrile
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine
  • 4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide