trans-N-Boc-4-(4-fluorobenzyl)-L-proline

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Names

[ CAS No. ]:
959583-52-9

[ Name ]:
trans-N-Boc-4-(4-fluorobenzyl)-L-proline

[Synonym ]:
(2S,4R)-4-[(4-fluorophenyl)methyl]-1-[(2-methylpropan-2-yl)oxycarbonyl]pyrrolidine-2-carboxylic acid

Chemical & Physical Properties

[ Molecular Formula ]:
C17H22FNO4

[ Molecular Weight ]:
323.35900

[ Exact Mass ]:
323.15300

[ PSA ]:
66.84000

[ LogP ]:
3.01630

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Di-tert-butyl dicarbonate
  • (2S,4R)-4-(4-Fluorobenzyl)pyrrolidine-2-carboxylic acid
  • (2S,4R)-di-tert-butyl 4-(4-fluorobenzyl)-5-oxopyrrolidine-1,2-dicarboxylate
  • (S)-N-Boc-2-pyrrolidone-5-carboxylic acid tert-butyl ester
  • (S)-tert-Butyl 5-oxopyrrolidine-2-carboxylate

DownStream

Related Compounds

  • 4-({1-[(2-Methoxyphenyl)methyl]piperidin-3-yl}methoxy)pyridine
  • N-{[1-(3-fluoro-4-methylbenzoyl)piperidin-4-yl]methyl}-3-methoxy-N-methylpyrazin-2-amine
  • 5-Bromo-2-({1-[(4-methoxyphenyl)methyl]piperidin-3-yl}methoxy)pyrimidine hydrochloride
  • 2-({1-[(3,5-Dimethoxyphenyl)methyl]piperidin-4-yl}oxy)-4-(trifluoromethyl)pyrimidine
  • 4-[5-(4-Ethylbenzenesulfonyl)-octahydropyrrolo[3,4-c]pyrrol-2-yl]-6-methylpyrimidine
  • 3-methoxy-N-methyl-N-({1-[(1,3,5-trimethyl-1H-pyrazol-4-yl)sulfonyl]piperidin-4-yl}methyl)pyrazin-2-amine
  • N-Methyl-N-[1-(6-phenylpyridazin-3-yl)azetidin-3-yl]ethanesulfonamide
  • 1-[4-(4-{[4-(Trifluoromethyl)pyrimidin-2-yl]oxy}piperidine-1-carbonyl)phenyl]pyrrolidine-2,5-dione
  • 3-(3-Fluorophenyl)-6-{4-[3-(methoxymethyl)-1,2,4-thiadiazol-5-yl]piperazin-1-yl}pyridazine
  • N-cyclopropyl-N-[1-(3-fluorobenzenesulfonyl)piperidin-4-yl]-6-methoxypyrimidin-4-amine
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