2-Amino-1-butanol

Suppliers

Names

[ CAS No. ]:
96-20-8

[ Name ]:
2-Amino-1-butanol

[Synonym ]:
2-Aminobutanol
2-aminobutan-1-ol
2-Amino-1-butanol
MFCD00008095
EINECS 202-488-2
1-Butanol, 2-amino-

Chemical & Physical Properties

[ Density]:
0.9±0.1 g/cm3

[ Boiling Point ]:
177.2±13.0 °C at 760 mmHg

[ Melting Point ]:
-2ºC

[ Molecular Formula ]:
C4H11NO

[ Molecular Weight ]:
89.136

[ Flash Point ]:
82.2±0.0 °C

[ Exact Mass ]:
89.084061

[ PSA ]:
46.25000

[ LogP ]:
-0.43

[ Vapour Pressure ]:
0.3±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.446

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
EK9625000
CHEMICAL NAME :
1-Butanol, 2-amino-
CAS REGISTRY NUMBER :
96-20-8
BEILSTEIN REFERENCE NO. :
1098274
LAST UPDATED :
199709
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C4-H11-N-O
MOLECULAR WEIGHT :
89.16
WISWESSER LINE NOTATION :
ZY2&1Q

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
2300 mg/kg
TOXIC EFFECTS :
Behavioral - tetany
REFERENCE :
20PKA3 "Novye Dannye Po Toksikologii Redkikh Metalov Ikh Soedinenii," New Data on the Toxicology of Rare Metals and Their Compounds, Izrael'son, Z.I., ed., Moscow, Izdatel'stvo "Meditsina," 1967 Volume(issue)/page/year: -,-,1967
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
250 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CBCCT* "Summary Tables of Biological Tests," National Research Council Chemical-Biological Coordination Center. (National Academy of Science Library, 2101 Constitution Ave., NW, Washington, DC 20418) Volume(issue)/page/year: 5,338,1953
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
316 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#00036

Safety Information

[ Symbol ]:

GHS05, GHS07, GHS09

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H302-H314-H400

[ Precautionary Statements ]:
P273-P280-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
C:Corrosive;

[ Risk Phrases ]:
R34

[ Safety Phrases ]:
S26-S36/37/39-S45

[ RIDADR ]:
UN 2735 8

[ WGK Germany ]:
2

[ RTECS ]:
EK9625000

[ Packaging Group ]:
III

[ Hazard Class ]:
8.0

Synthetic Route

Precursor & DownStream

Precursor

  • 2-Aminobutanoic acid
  • 1-Butanol, 2-nitro-
  • tert-Butyl (1-hydroxybutan-2-yl)carbamate
  • ethyl (2E)-2-hydroxyiminobutanoate
  • 2-Amino-3-buten-1-ol
  • 1-isobutoxymethyl-propylamine
  • METHYL 2-AMINOBUTANOATE HYDROCHLORIDE
  • cyclohexyl 4-[[5-[3-(trifluoromethyl)phenyl]furan-2-carbonyl]amino]benzoate
  • Methanol
  • 1,3-Propanediol,2-ethyl-2-nitro-

DownStream

  • 4,5,7-triethyl-2,2,3-trimethyl-6-oxa-1-azonia-2-sila-5-boratabicyclo{3.3.0}oct-3-ene
  • 4,5,7-triethyl-2,2,3-trimethyl-1-oxa-6-aza-2-sila-5-bora-3-cyclooctene
  • methylamine
  • 2-Thiazolidinethione,4-ethyl-
  • SELICICLIB
  • 2-Aminobutanoic acid
  • (R)-(-)-2-Amino-1-butanol
  • Isobutanol-2-amine
  • Carbamic acid,[1-(hydroxymethyl)propyl]-, ethyl ester (6CI,7CI,8CI,9CI)
  • N-(1-hydroxybutan-2-yl)benzamide

Articles

Universal spectropolarimeter based on overtone circular dichroism measurements in the near-infrared region.

Anal. Chem. 66(21) , 3639-43, (1994)

A novel and highly sensitive circular dichroism spectropolarimeter for the near-infrared region has been developed. In this instrument, a solid state titanium-sapphire laser that can be spectrally tun...

Role for phospholipid interactions in the trafficking defect of Delta F508-CFTR.

Biochemistry 41(37) , 11161-70, (2002)

Cystic fibrosis commonly occurs as a consequence of the DeltaF508 mutation in the first nucleotide binding fold domain (NBF-1) of CFTR. The mutation causes retention of the mutant CFTR molecule in the...

Comparison of the cellular and biochemical properties of Plasmodium falciparum choline and ethanolamine kinases.

Biochem. J. 425(1) , 149-58, (2010)

The proliferation of the malaria-causing parasite Plasmodium falciparum within the erythrocyte is concomitant with massive phosphatidylcholine and phosphatidylethanolamine biosynthesis. Based on pharm...


More Articles


Related Compounds

  • 2-Amino-1-butanol
  • 2-amino-1-butanol
  • (2R)-2-Amino-1-butanol
  • (2S)-2-Amino-1-butanol
  • N-Cbz-2-amino-1-butanol
  • N-Boc-2-amino-1-butanol
  • 1-(2-Aminoethyl)-3H-indol-2-one;hydrochloride
  • Methyl 2-(5,5-dimethylpyrrolidin-3-yl)acetate;hydrochloride
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • Tert-butyl3-(isocyanatomethyl)piperidine-1-carboxylate
  • 2-(5-Fluoro-2-methylphenyl)prop-2-enoic acid
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • 3-[5-(3,3-Diethoxyprop-1-ynyl)-1-oxo-isoindolin-2-yl]piperidine-2,6-dione
  • 2-(2-Chloroethyl)-5-methoxypyridine