1,3-Dibromo-2-propanol

Names

[ CAS No. ]:
96-21-9

[ Name ]:
1,3-Dibromo-2-propanol

[Synonym ]:
EINECS 202-489-8
MFCD00000216
1,3-dibromopropan-2-ol
1,3-Dibromo-2-propanol
2-Propanol, 1,3-dibromo-

Chemical & Physical Properties

[ Density]:
2.1±0.1 g/cm3

[ Boiling Point ]:
194.3±0.0 °C at 760 mmHg

[ Molecular Formula ]:
C₃H₆Br₂O

[ Molecular Weight ]:
217.887

[ Flash Point ]:
46.7±0.0 °C

[ Exact Mass ]:
215.878525

[ PSA ]:
20.23000

[ LogP ]:
1.48

[ Vapour Pressure ]:
0.1±0.8 mmHg at 25°C

[ Index of Refraction ]:
1.556

[ Storage condition ]:
Refrigerator

[ Water Solubility ]:
soluble

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UB0200000

CHEMICAL NAME :: 2-Propanol, 1,3-dibromo-

CAS REGISTRY NUMBER :: 96-21-9

BEILSTEIN REFERENCE NO. :: 1732074

LAST UPDATED :: 199710

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C3-H6-Br2-O

MOLECULAR WEIGHT :: 217.91

WISWESSER LINE NOTATION :: E1YQ1E

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 150 mg/kg

TOXIC EFFECTS :: Tumorigenic - protects against induction of experimental tumors

MUTATION DATA

TYPE OF TEST :: DNA inhibition

TEST SYSTEM :: Human HeLa cell

DOSE/DURATION :: 1600 umol/L

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 92,427,1982

Safety Information

[ Symbol ]:

GHS02, GHS06, GHS08

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H226-H301-H315-H319-H335-H351

[ Precautionary Statements ]:
P261-P281-P301 + P310-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
T:Toxic;Xn:Harmful;

[ Risk Phrases ]:
R10;R24/25;R36/37/38;R68

[ Safety Phrases ]:
S16-S26-S36/37/39-S45

[ RIDADR ]:
UN 1987 3/PG 3

[ WGK Germany ]:
3

[ RTECS ]:
UB0200000

[ Packaging Group ]:
II

[ Hazard Class ]:
3.2

[ HS Code ]:
2905590090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Epibromohydrin
acrolein
Allyl alcohol
1,3-bis(phenylsulfanyl)propan-2-ol
1,3-Dibromo-2-propanone
tert-butyl-(1,3-dibromopropan-2-yloxy)-dimethylsilane
Bromodinitromethane
Bromoacetic acid
TRIBROMOHYDRIN
1,3-dibromo-1-propene

Customs

[ HS Code ]: 2905590090

[ Summary ]:
2905590090 other halogenated, sulphonated, nitrated or nitrosated derivatives of acyclic alcohols。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

Articles

Syntheses, calcium channel agonist-antagonist modulation activities, and nitric oxide release studies of nitrooxyalkyl 1,4-dihydro-2,6-dimethyl-3-nitro-4-(2,1,3-benzoxadiazol-4-yl)pyridine-5-carboxylate racemates, enantiomers, and diastereomers.

J. Med. Chem. 47(1) , 254-61, (2004)

A novel group of hybrid calcium channel (CC) modulators was prepared where the isopropyl ester moiety of isopropyl 1,4-dihydro-2,6-dimethyl-3-nitro-4-(2,1,3-benzoxadiazol-4-yl)pyridine-5-carboxylate (...

Sugar-pendant diamines.

J. Org. Chem. 66(11) , 3783-9, (2001)

A set of 1,3-propanediamine derivatives connected to carbohydrates (5) has been prepared in four steps from peracetylated sugar and 1,3-dibromo-2-propanol in 60-73% yields. D-Glucose, D-mannose, D-gal...

Palladium-phosphorus/sulfur nanoparticles (NPs) decorated on graphene oxide: synthesis using the same precursor for NPs and catalytic applications in Suzuki-Miyaura coupling.

Nanoscale 6(9) , 4588-97, (2014)

PdP2 and Pd4S nanoparticles (NPs) (size: ∼2-6 and 9-15 nm respectively) have been prepared for the first time from a single source precursor complex [Pd(L)Cl2] (1) by its one pot thermolysis at 200 °C...