Lactobionic acid

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Names

[ CAS No. ]:
96-82-2

[ Name ]:
Lactobionic acid

[Synonym ]:
EINECS 202-538-3
D-gluconic acid, 4-O-b-D-galactopyranosyl-
D-Gluconic acid, 4-O-β-D-galactopyranosyl-
LactobionS
LACTOBIONIC ACID(RG)
4-O-β-D-Galactopyranosyl-D-gluconic acid
LaCLobionic Acid
LACTOBIONIC ACID POWDER
LACTOBIONIC ACID FREE ACID
4-O-b-D-galactopyranosyl-D-gluconic acid
4-(b-D-Galactosido)-D-gluconic Acid
MFCD00078147
Lactobionic acid
(2R,3R,4R,5R)-2,3,5,6-Tetrahydroxy-4-{[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}hexanoic acid

Chemical & Physical Properties

[ Density]:
1.8±0.1 g/cm3

[ Boiling Point ]:
864.7±65.0 °C at 760 mmHg

[ Melting Point ]:
113-118 °C(lit.)

[ Molecular Formula ]:
C12H22O12

[ Molecular Weight ]:
358.296

[ Flash Point ]:
319.1±27.8 °C

[ Exact Mass ]:
358.111115

[ PSA ]:
217.60000

[ LogP ]:
-4.06

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.648

[ Water Solubility ]:
10 g/100 mL

MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
1

[ HS Code ]:
2932999099

Synthetic Route

Precursor & DownStream

Precursor

  • Cellobiose
  • Lactose
  • (3R,4R,5S,6R)-3,4-dihydroxy-6-(hydroxymethyl)-5-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-one
  • 3-O-BETA-D-GALACTO-PYRANOSYL-D-ARABINOSE

DownStream

  • n-2,10-dion(1:1)

Customs

[ HS Code ]: 2932999099

[ Summary ]:
2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Galactosylated pullulan-curcumin conjugate micelles for site specific anticancer activity to hepatocarcinoma cells.

Colloids Surf. B Biointerfaces 133 , 347-55, (2015)

Galactosylated pullulan-curcumin conjugate (LANH2-Pu Ald-Cur SA) is developed for target specific delivery of curcumin to hepatocarcinoma cells by five step synthetic strategy, which includes oxidatio...

Galactosylated nanostructured lipid carriers for delivery of 5-FU to hepatocellular carcinoma.

J. Liposome Res. 22(3) , 224-36, (2012)

The aim of the present study was to design a targeted delivery system of 5-fluorouracil (5-FU) for hepatocellular carcinoma (HCC). Lactobionic acid (LB) was conjugated to stearyl amine (SA) by a chemi...

Targeting liver cancer via ASGP receptor using 5-FU-loaded surface-modified PLGA nanoparticles.

J. Microencapsul. 31(5) , 479-87, (2014)

Liver cancer is widespread liver malignancy in the world, for an estimated one million deaths annually.In present work, lactobionic acid conjugated PLGA nanoparticles (LDNPs) bearing 5-Fluorouracil (5...


More Articles


Related Compounds

  • Lactobionic acid sodium
  • Lactobionic Acid Calcium Salt
  • Lactobionic Acid Calcium Salt
  • lactobionic acid,compd. with erythromycin
  • Octanethioic acid S-propyl ester
  • Hexanethioic acid S-decyl ester
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • 3-(4-chlorobenzyl)-N-(3-fluoro-4-methylphenyl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decane-8-carboxamide
  • tert-Butyl-DL-alanine
  • 4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide