2'-Deoxyguanosine

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Names

[ CAS No. ]:
961-07-9

[ Name ]:
2'-Deoxyguanosine

[Synonym ]:
MFCD00080300
A-2'-DEOXYGUANOSINE
DEOXYGUANOSINE-2'
2'-Deoxyguanosinemonohydrate
guaninedeoxyriboside
2'-DEOXY-D-GUANOSINE
Desoxyguanosine
deoxyguanosine
2'-Deoxyguanosine monohydrate
EINECS 213-505-8

Chemical & Physical Properties

[ Density]:
2.1±0.1 g/cm3

[ Boiling Point ]:
706.6±70.0 °C at 760 mmHg

[ Melting Point ]:
300 °C

[ Molecular Formula ]:
C₁₀H₁₃N₅O₄

[ Molecular Weight ]:
267.241

[ Flash Point ]:
381.2±35.7 °C

[ Exact Mass ]:
267.096741

[ PSA ]:
148.51000

[ LogP ]:
-2.91

[ Vapour Pressure ]:
0.0±2.4 mmHg at 25°C

[ Index of Refraction ]:
1.907

[ Storage condition ]:
Store at RT.

[ Water Solubility ]:
NH4OH 1 M: 50 mg/mL, clear to very faintly turbid, yellow to brown

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: MF8760000

CHEMICAL NAME :: Guanosine, 2'-deoxy-

CAS REGISTRY NUMBER :: 961-07-9

LAST UPDATED :: 199701

DATA ITEMS CITED :: 8

MOLECULAR FORMULA :: C10-H13-N5-O4

MOLECULAR WEIGHT :: 267.28

WISWESSER LINE NOTATION :: T56 BN DN FMYMVJ GUM D- ET5OTJ B1Q CQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >800 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :: DNA damage

TEST SYSTEM :: Mammal - species unspecified Lymphocyte

DOSE/DURATION :: 50 mmol/L

REFERENCE :: PNASA6 Proceedings of the National Academy of Sciences of the United States of America. (National Academy of Sciences, Printing & Pub. Office, 2101 Constitution Ave., Washington, DC 20418) V.1- 1915- Volume(issue)/page/year: 48,686,1962 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X1005 No. of Facilities: 35 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 115 (estimated) No. of Female Employees: 64 (estimated)

Safety Information

[ Hazard Codes ]:
F+

[ Safety Phrases ]:
S24/25

[ WGK Germany ]:
3

[ RTECS ]:
MF8760000

[ HS Code ]:
2934999090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

2,6-Diaminopurine 2'-deoxyriboside
2-AMINO-6-CHLORO-9-(BETA-D-2-DEOXYRIBOFURANOSYL)PURINE
8,2'-anhydro-8-mercaptoguanosine
N-(9-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)picolinamide
5'-Guanylic acid
Thymidine
8-Bromo-2'-deoxyguanosine
2-fluoro-2'-deoxyinosine
2-N-(2,2'-bis(2-nitrophenyl)ethyloxycarbonyl)-2'-deoxyguanosine
2-N-bis(2,2'-bis(2-nitrophenyl)ethyloxycarbonyl)-2'-deoxyguanosine

DownStream

N2-Benzoyl-2'-deoxy-5'-O-DMT-D-guanosine
2'-Deoxyisoguanosine
Cladribine
8-hydroxyguanosine
8-hydroxy-2'-deoxyguanosine
N6-benzoyl-2'-Deoxyadenosine
2,6-Diaminopurine 2'-deoxyriboside
2-Deoxy-D-ribose
2'-Deoxy-5'-Guanylic Acid
2-AMINO-9-((2R,4S,5S)-4-HYDROXY-5-(HYDROXYMETHYL)TETRAHYDROFURAN-2-YL)-3H-PURIN-6(9H)-ONE

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%