N'-benzyl-N,N-dimethyl-N'-phenylethane-1,2-diamine

Names

[ CAS No. ]:
961-71-7

[ Name ]:
N'-benzyl-N,N-dimethyl-N'-phenylethane-1,2-diamine

[Synonym ]:
Lergitin
Antergan
RP 2339
Bridal
N-benzyl-N',N'-dimethyl-N-phenyl-ethylenediamine
Dimetina
2339 RP
Phenbenzamin
PHENBENZAMINE
N-Benzyl-N',N'-dimethyl-N-phenyl-aethylendiamin
PM 245

Chemical & Physical Properties

[ Density]:
1.038g/cm3

[ Boiling Point ]:
375.9ºC at 760mmHg

[ Molecular Formula ]:
C₁₇H₂₂N₂

[ Molecular Weight ]:
254.37000

[ Flash Point ]:
166.2ºC

[ Exact Mass ]:
254.17800

[ PSA ]:
6.48000

[ LogP ]:
3.25480

[ Index of Refraction ]:
1.59

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: KV1915000

CHEMICAL NAME :: Ethylenediamine, N-benzyl-N',N'-dimethyl-N-phenyl-

CAS REGISTRY NUMBER :: 961-71-7

BEILSTEIN REFERENCE NO. :: 2738634

LAST UPDATED :: 199612

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C17-H22-N2

MOLECULAR WEIGHT :: 254.41

WISWESSER LINE NOTATION :: 1N1&2NR&1R

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 120 mg/kg

TOXIC EFFECTS :: Behavioral - tremor Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - cyanosis

REFERENCE :: BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK) V.1-33, 1946-68. For publisher information, see BJPCBM. Volume(issue)/page/year: 11,1,1956

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intramuscular

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 350 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FRPSAX Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia, Italy) V.8-43 1953-88 For publisher information, see FRMCE8 Volume(issue)/page/year: 13,3,1958

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 170 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FRPSAX Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia, Italy) V.8-43 1953-88 For publisher information, see FRMCE8 Volume(issue)/page/year: 13,3,1958

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 175 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: THERAP Therapie. (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris, France) V.1- 1946- Volume(issue)/page/year: 12,412,1957

Safety Information

[ HS Code ]:
2921590090

Synthetic Route

Click to get detail synthetic route

Customs

[ HS Code ]: 2921590090

[ Summary ]:
2921590090. other aromatic polyamines and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Related Compounds

N'-benzyl-N,N-dimethyl-N'-phenylethane-1,2-diamine,hydrochloride
N'-benzyl-N,N-dimethyl-N'-pyrimidin-4-ylethane-1,2-diamine
Tripelennamine
TRIPELENNAMINE CITRATE
Midamaline
1,2-Ethanediamine,N1,N1-dimethyl-N2-(phenylmethyl)-N2-2-quinolinyl-, hydrochloride (1:2)
4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
4-(5,6-Dichloro-4-pyrimidinyl)morpholine
2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
(4-Methyl-tetrahydro-furan-2-yl)-methanol
N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
tert-Butyl-DL-alanine
2-(3-Cyano-4-hydroxy-2-methyl-2-cyclopenten-1-ylidene)hydrazinecarboxamide