7,9-dimethylbenzo[c]acridine

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Names

[ CAS No. ]:
963-89-3

[ Name ]:
7,9-dimethylbenzo[c]acridine

[Synonym ]:
3,10-Dimethyl-7,8-benzacridine [French]
7,9-Dimethyl-benz[c]acridin
7,9-Dimethyl-benzo<c>acridin
MFCD00192074
3,10-Dimethyl-7,8-benzoacridin
7,9-dimethyl-benzo[c]acridine
7,9-dimethyl-benz[c]acridine
Benz(c)acridine,7,9-dimethyl

Chemical & Physical Properties

[ Density]:
1.182g/cm3

[ Boiling Point ]:
300ºC10 mm Hg(lit.)

[ Melting Point ]:
157-161ºC(lit.)

[ Molecular Formula ]:
C19H15N

[ Molecular Weight ]:
257.32900

[ Flash Point ]:
208.7ºC

[ Exact Mass ]:
257.12000

[ PSA ]:
12.89000

[ LogP ]:
5.15800

[ Index of Refraction ]:
1.737

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
CU3480000
CHEMICAL NAME :
Benz(c)acridine, 7,9-dimethyl-
CAS REGISTRY NUMBER :
963-89-3
BEILSTEIN REFERENCE NO. :
0192241
LAST UPDATED :
199710
DATA ITEMS CITED :
15
MOLECULAR FORMULA :
C19-H15-N
MOLECULAR WEIGHT :
257.35
WISWESSER LINE NOTATION :
T D6 B666 CNJ G1 J1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
180 mg/kg/15W-I
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Lungs, Thorax, or Respiration - chronic pulmonary edema Lungs, Thorax, or Respiration - bronchiolar constriction
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
200 mg/kg/4W-I
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Tumorigenic - tumors at site of application
TYPE OF TEST :
TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
250 mg/kg/10D-I
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Tumorigenic - tumors at site of application

MUTATION DATA

TYPE OF TEST :
Morphological transformation
TEST SYSTEM :
Rodent - hamster Embryo
DOSE/DURATION :
100 ug/L
REFERENCE :
JJIND8 JNCI, Journal of the National Cancer Institute. (Washington, DC) V.61-79, 1978-87. For publisher information, see JNCIEQ. Volume(issue)/page/year: 67,1303,1981

Safety Information

[ Hazard Codes ]:
T: Toxic;

[ Risk Phrases ]:
45-46-20/21/22-36/37/38

[ Safety Phrases ]:
S22;S26;S45;S53;S36/S37/S39

[ HS Code ]:
2933990090

Synthetic Route

Precursor & DownStream

Precursor

  • 1-Naphthalenamine,N-(4-methylphenyl)-
  • Ethanoic anhydride

DownStream

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%


Related Compounds

  • 5-fluoro-7,9-dimethylbenzo[c]acridine
  • 7,10-Dimethylbenzo[c]acridine
  • 7,9-DIMETHYLBENZ[C]ACRIDINE-5,6-OXIDE
  • 7,9,10-Trimethylbenz[c]acridine
  • 7,9,11-Trimethylbenz[c]acridine
  • 7,9,11-Triethylbenz[c]acridine
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • 1-isopropyl-6-(4-pyridyl)imidazo[1,2-b]pyrazole
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine
  • 4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide