2,6-dichloro-5-fluoronicotinoyl chloride

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Names

[ CAS No. ]:
96568-02-4

[ Name ]:
2,6-dichloro-5-fluoronicotinoyl chloride

[Synonym ]:
2,6-dichloro-5-fluoronicotinoyl chloride
MFCD01863240
2,6-dichloro-5-fluoro-pyridine-3-carboxylic acid chloride
2,6-dichloro-5-fluoronicotinyl chloride
2,6-Dichloro-5-fluoro-3-pyridinecarbonyl chloride
2,6-dichloro-5-fluoronicotinic acid chloride
2,6-dichloro-5-fluoropyridinecarbonyl chloride
nicotinyl chloride

Chemical & Physical Properties

[ Density]:
1.640 g/mL at 25 °C(lit.)

[ Boiling Point ]:
238-239 °C(lit.)

[ Molecular Formula ]:
C6HCl3FNO

[ Molecular Weight ]:
228.43600

[ Flash Point ]:
>230 °F

[ Exact Mass ]:
226.91100

[ PSA ]:
29.96000

[ LogP ]:
2.90650

[ Index of Refraction ]:
n20/D >1.5720(lit.)

[ Storage condition ]:
0-6°C

MSDS

Click to get detail MSDS

Safety Information

[ Hazard Codes ]:
C: Corrosive;

[ Risk Phrases ]:
34

[ Safety Phrases ]:
S26-S36/37/39-S45

[ RIDADR ]:
UN 3265 8/PG 2

[ WGK Germany ]:
3

[ HS Code ]:
2933399090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 2,6-Dichloro-5-fluoronicotinic acid
  • ethyl 2,6-dichloro-5-fluoropyridine-3-carboxylate
  • 2,6-Dichloro-5-fluoronicotinonitrile
  • 2,6-Dichloro-5-fluoronicotinamide

DownStream

  • ethyl 6-fluoro-1-(4-fluorophenyl)-7-(4-methylpiperazin-1-yl)-4-oxo-1,8-naphthyridine-3-carboxylate
  • Tosufloxacin pharmaceutical intermediate
  • ethyl 2,6-dichloro-5-fluoropyridine-3-carboxylate
  • Ethyl 2,6-dichloro-5-fluoro-pyridine-3-acetoacetate
  • Ethyl 7-chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylate
  • ethyl 1-(2,4-difluorophenyl)-6-fluoro-7-(3-methylpiperazin-1-yl)-4-oxo-1,8-naphthyridine-3-carboxylate
  • ethyl 6-fluoro-1-(4-fluorophenyl)-7-(3-methylpiperazin-1-yl)-4-oxo-1,8-naphthyridine-3-carboxylate
  • ethyl 1-(2,4-difluorophenyl)-6-fluoro-7-(4-methylpiperazin-1-yl)-4-oxo-1,8-naphthyridine-3-carboxylate
  • ethyl 7-chloro-6-fluoro-1-(4-fluorophenyl)-4-oxo-1,8-naphthyridine-3-carboxylate
  • Ethyl-2-(2,6-dichlor-5-fluorpyridin-3-carbonyl)-3-(2,4-difluorphenylamino)-acrylat

Customs

[ HS Code ]: 2933399090

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

  • 2,6-dichloro-5-fluoronicotinoyl chloride
  • ethyl 2-hydrazono-2-(2,6-dichloro-5-fluoronicotinoyl)acetate
  • ethyl 2-diazo-2-(2,6-dichloro-5-fluoronicotinoyl)acetate
  • 2,6-DICHLORO-5-FLUORO-N-ISOPROPYLNICOTINAMIDE
  • 2,6-dichloro-5-ethyl-4-methylpyridine-3-carboxylic acid
  • 2,6-dichloro-5-methoxy-4-vinylpyrimidine
  • 4-Iodothieno[2,3-c]pyridin-7-ol
  • 3-(2-Bromo-5-hydroxyphenyl)-2-cyanoprop-2-enamide
  • 5-amino-4-(4,5-dimethyl-1,3-thiazol-2-yl)-1-(2-phenylethyl)-1,2-dihydro-3H-pyrrol-3-one
  • 1-(2-fluorophenyl)-5-imino-4-[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]-2,5-dihydro-1H-pyrrol-3-ol
  • 6-[4-hydroxy-2-imino-3-(4-phenyl-1,3-thiazol-2-yl)-2,5-dihydro-1H-pyrrol-1-yl]-2H-chromen-2-one
  • Acetamide, N-[3-[2-amino-3-[4-(3,4-dimethoxyphenyl)-2-thiazolyl]-4,5-dihydro-4-oxo-1H-pyrrol-1-yl]phenyl]-
  • 5-amino-1-(2-isopropylphenyl)-4-[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]-1,2-dihydro-3H-pyrrol-3-one
  • 5-amino-1-cyclooctyl-4-(4-phenyl-1,3-thiazol-2-yl)-1,2-dihydro-3H-pyrrol-3-one
  • 5-amino-1-phenyl-4-(4-phenyl-1,3-thiazol-2-yl)-1,2-dihydro-3H-pyrrol-3-one
  • Ethyl 7-(4-hydroxy-3-methoxyphenyl)-2-[(2-methoxy-2-oxoethyl)sulfanyl]-5-methyl-4,7-dihydro[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxylate
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