2,6-dichloro-5-fluoronicotinoyl chloride

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Names

[ Name ]:
2,6-dichloro-5-fluoronicotinoyl chloride

[Synonym ]:
2,6-dichloro-5-fluoronicotinoyl chloride
MFCD01863240
2,6-dichloro-5-fluoro-pyridine-3-carboxylic acid chloride
2,6-dichloro-5-fluoronicotinyl chloride
2,6-Dichloro-5-fluoro-3-pyridinecarbonyl chloride
2,6-dichloro-5-fluoronicotinic acid chloride
2,6-dichloro-5-fluoropyridinecarbonyl chloride
nicotinyl chloride

Chemical & Physical Properties

[ Density]:
1.640 g/mL at 25 °C(lit.)

[ Boiling Point ]:
238-239 °C(lit.)

[ Molecular Formula ]:
C₆HCl₃FNO

[ Molecular Weight ]:
228.43600

[ Flash Point ]:
>230 °F

[ Exact Mass ]:
226.91100

[ PSA ]:
29.96000

[ LogP ]:
2.90650

[ Index of Refraction ]:
n20/D >1.5720(lit.)

[ Storage condition ]:
0-6°C

MSDS

Click to get detail MSDS

Safety Information

[ Hazard Codes ]:
C: Corrosive;

[ Risk Phrases ]:
34

[ Safety Phrases ]:
S26-S36/37/39-S45

[ RIDADR ]:
UN 3265 8/PG 2

[ WGK Germany ]:
3

[ HS Code ]:
2933399090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

2,6-Dichloro-5-fluoronicotinic acid
ethyl 2,6-dichloro-5-fluoropyridine-3-carboxylate
2,6-Dichloro-5-fluoronicotinonitrile
2,6-Dichloro-5-fluoronicotinamide

DownStream

ethyl 6-fluoro-1-(4-fluorophenyl)-7-(4-methylpiperazin-1-yl)-4-oxo-1,8-naphthyridine-3-carboxylate
Tosufloxacin pharmaceutical intermediate
ethyl 2,6-dichloro-5-fluoropyridine-3-carboxylate
Ethyl 2,6-dichloro-5-fluoro-pyridine-3-acetoacetate
Ethyl 7-chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylate
ethyl 1-(2,4-difluorophenyl)-6-fluoro-7-(3-methylpiperazin-1-yl)-4-oxo-1,8-naphthyridine-3-carboxylate
ethyl 6-fluoro-1-(4-fluorophenyl)-7-(3-methylpiperazin-1-yl)-4-oxo-1,8-naphthyridine-3-carboxylate
ethyl 1-(2,4-difluorophenyl)-6-fluoro-7-(4-methylpiperazin-1-yl)-4-oxo-1,8-naphthyridine-3-carboxylate
ethyl 7-chloro-6-fluoro-1-(4-fluorophenyl)-4-oxo-1,8-naphthyridine-3-carboxylate
Ethyl-2-(2,6-dichlor-5-fluorpyridin-3-carbonyl)-3-(2,4-difluorphenylamino)-acrylat

Customs

[ HS Code ]: 2933399090

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

2,6-dichloro-5-fluoronicotinoyl chloride
ethyl 2-hydrazono-2-(2,6-dichloro-5-fluoronicotinoyl)acetate
ethyl 2-diazo-2-(2,6-dichloro-5-fluoronicotinoyl)acetate
2,6-DICHLORO-5-FLUORO-N-ISOPROPYLNICOTINAMIDE
2,6-dichloro-5-ethyl-4-methylpyridine-3-carboxylic acid
2,6-dichloro-5-methoxy-4-vinylpyrimidine
(4-(6-(Thiophen-2-yl)pyridazin-3-yl)piperazin-1-yl)(2-(trifluoromethyl)phenyl)methanone
N-(2-(3-(4-ethoxyphenyl)-6-oxopyridazin-1(6H)-yl)ethyl)-4-methylbenzenesulfonamide
N-(2-(3-(4-ethoxyphenyl)-6-oxopyridazin-1(6H)-yl)ethyl)-4-fluorobenzenesulfonamide
2-(Difluoromethyl)-1-fluoro-3-nitrobenzene
2-[[1-(3,4-Dihydro-3-oxo-2H-1,4-benzoxazin-6-yl)ethyl]amino]propanamide
4-((5-Chlorothiophen-2-yl)methyl)piperazin-2-one
3-Fluoro-4'-(trifluoromethyl)biphenyl
(4-(3-(3-fluorophenyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)piperazin-1-yl)(2-(trifluoromethyl)phenyl)methanone
(4-(3-(3-fluorophenyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)piperazin-1-yl)(3-(trifluoromethyl)phenyl)methanone
[1,1'-biphenyl]-4-yl(4-(3-(3-fluorophenyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)piperazin-1-yl)methanone

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