U-69593

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Names

[ CAS No. ]:
96744-75-1

[ Name ]:
U-69593

[Synonym ]:
Trp-1
Trytophan pyrolysate 1
1,4-Dimethyl-9H-pyrido(4,3-b)indol-3-amine
[3H]-Trp-P-1
Tryptophan P1
[14C]-Trp-P-1
Trp-P-1
3-AMINO-1,4-DIMETHYL-5H-PYRIDO(4,3-B)INDOLE
U-69593

Chemical & Physical Properties

[ Density]:
1.14g/cm3

[ Boiling Point ]:
518.719ºC at 760 mmHg

[ Molecular Formula ]:
C22H32N2O2

[ Molecular Weight ]:
356.50

[ Flash Point ]:
267.512ºC

[ Exact Mass ]:
356.24600

[ PSA ]:
32.78000

[ LogP ]:
3.19150

[ Index of Refraction ]:
1.581

[ Storage condition ]:
2-8°C

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Articles

Comparison of liquid chromatography-mass spectrometry and radioimmunoassay for measurement of fentanyl and determination of pharmacokinetics in equine plasma.

J. Anal. Toxicol. 32(9) , 754-9, (2008)

This study evaluated the validity of measuring fentanyl concentrations in equine plasma using radioimmunoassay (RIA) by comparing it to the established technique of liquid chromatography-mass spectrom...

Physical presence of nor-binaltorphimine in mouse brain over 21 days after a single administration corresponds to its long-lasting antagonistic effect on κ-opioid receptors.

J. Pharmacol. Exp. Ther. 346(3) , 545-54, (2013)

In the mouse 55°C warm-water tail-withdrawal assay, a single administration of nor-binaltorphimine (nor-BNI; 10 mg/kg i.p.) antagonized κ-opioid receptor (KOR) agonist-induced antinociception up to 14...

Repeated stress dysregulates κ-opioid receptor signaling in the dorsal raphe through a p38α MAPK-dependent mechanism.

J. Neurosci. 32(36) , 12325-36, (2012)

Repeated stress releases dynorphins and causes subsequent activation of κ-opioid receptors (KORs) in limbic brain regions. The serotonergic dorsal raphe nucleus (DRN) has previously been found to be a...


More Articles


Related Compounds

  • U-104
  • U 19451A
  • [(U(N(CH2CH2NSiMe3)3))2(μ-O)]
  • U-48800
  • U-89843A
  • U-(13)C-phenanthrene
  • 1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl 2-(3-methylcyclopentyl)acetate
  • 1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl (2S)-1-methylpiperidine-2-carboxylate
  • 1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl 1,3-dimethylcyclopentane-1-carboxylate
  • 1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl 4-methylidenecyclohexane-1-carboxylate
  • 1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl 3-cyclopropylpentanoate
  • 1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl 5-chloro-1-methyl-1H-pyrazole-3-carboxylate
  • 1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl 4-fluorooxane-4-carboxylate
  • 1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl 5-ethyl-1,3-thiazole-4-carboxylate
  • 1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl 2-(4-chlorophenyl)-1,3-thiazole-5-carboxylate
  • 2-(2-amino-1H-imidazol-1-yl)acetonitrile
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