(2R)-2-[(2S,3S)-3-{(1R)-1-(t-butyldimethylsilyloxy)ethyl}-4-oxoazetidin-2-yl]propionic acid

Names

[ CAS No. ]:
97101-07-0

[ Name ]:
(2R)-2-[(2S,3S)-3-{(1R)-1-(t-butyldimethylsilyloxy)ethyl}-4-oxoazetidin-2-yl]propionic acid

[Synonym ]:
.(3S,4S)-3-[(R)-1-(tert-butyldimethylsilyloxy)ethyl]-4-[(R)-1-carboxyethyl]-2-azetidinone
.(3S,4S)-3-[(1R)-(t-butyldimethyl-silyloxy)ethyl]-4-[(1R)-1-carboxyethyl]-2-azetidinone
.(3S,4S)-[(R)-1'-((tert-butyldimethylsilyl)oxy)ethyl]-4-[(R)-1-carboxyethyl]-2-azetidinone
.(3S,4S)-3-[(R)-1-(t-butyldimethylsilyloxy)ethyl]-4-[(R)-1-carboxyethyl]azetidin-2-one
(R)-2-[(3S,4S)-3-[(R)-1-tert-butyldimethylsilyloxyethyl]-2-oxoazetidin-4-yl]propionic acid
.(3S,4S)-3-[(1'R)-1'-(tert-butyldimethylsilyloxy)ethyl]-4-[1'-carboxyethyl]azetidin-2-one

Chemical & Physical Properties

[ Molecular Formula ]:
C14H27NO4Si

[ Molecular Weight ]:
301.45400

[ Exact Mass ]:
301.17100

[ PSA ]:
75.63000

[ LogP ]:
2.56080

Synthetic Route

Precursor & DownStream

Precursor

  • 1-((R)-2-((2R,3S)-3-((R)-1-((tert-butyldimethylsilyl)oxy)ethyl)-4-oxoazetidin-2-yl)propanoyl)-4,4,5,5-tetramethyl-3-propionylimidazolidin-2-one
  • (3S,4R)-3-[(R)-1-(t-Butyldimethylsilyloxy)ethyl]-4-[(R)-1-(4,4-dibutyl-5,5-pentamethylene-2-oxazolidone-3-carbonyl)ethyl]-2-azetidinone

DownStream

  • 4-nitrobenzyl (4R,5R,6S)-6-[(1R)-1-hydroxyethyl]-4-methyl-3,7-dioxo-1-azabicyclo[3.2.0]-heptane-2-carboxylate
  • (3S,4S)-1-(tert-butoxycarbonylmethyl)-3-[(1R)-1-tert-butyldimethylsilyloxyethyl]-4-[(1R)-1-carboxyethyl]-2-azetidinone
  • (3S,4S)-1-(tert-butoxycarbonylmethyl)-3-[(1R)-1-tert-butyldimethylsilyloxyethyl]-4-[(1R)-1-phenylthiocarbonylethyl]-2-azetidinone
  • (3S,4S)-1-(p-nitrobenzyloxycarbonylmethyl)-4-[(1R)-1-phenylthiocarbonylethyl]-3-[(1R)-1-trimethylsilyloxyethyl]-2-azetidinone