FLB 131

Suppliers

Names

[ Name ]:
FLB 131

[Synonym ]:
(2S)-2-{[(3-Chloro-5-ethyl-6-hydroxy-2-methoxybenzoyl)amino]methyl}-1-ethylpyrrolidinium chloride
3-Chloro-5-ethyl-N-{[(2S)-1-ethylpyrrolidin-2-yl]methyl}-6-hydroxy-2-methoxybenzamide hydrochloride (1:1)
Pyrrolidinium, 2-[[(3-chloro-5-ethyl-6-hydroxy-2-methoxybenzoyl)amino]methyl]-1-ethyl-, chloride, (2S)- (1:1)
MFCD00055132

Chemical & Physical Properties

[ Melting Point ]:
144 - 146 °C

[ Molecular Formula ]:
C₁₇H₂₆Cl₂N₂O₃

[ Molecular Weight ]:
377.306

[ Exact Mass ]:
376.132050

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ RTECS ]:
CV2450000

Articles

Dopamine D2 receptor activity modulates Akt signaling and alters GABAergic neuron development and motor behavior in zebrafish larvae.

J. Neurosci. 31 , 5512-25, (2011)

An imbalance in dopamine-mediated neurotransmission is a hallmark physiological feature of neuropsychiatric disorders, such as schizophrenia. Recent evidence demonstrates that dopamine D(2) receptors,...

Dopamine D2 receptors are involved in the regulation of Fyn and metabotropic glutamate receptor 5 phosphorylation in the rat striatum in vivo.

J. Neurosci. Res. 94 , 329-38, (2016)

Fyn, a major Src family kinase (SFK) member that is densely expressed in striatal neurons, is actively involved in the regulation of cellular and synaptic activities in local neurons. This SFK member ...

Some in vitro receptor binding properties of [3H]eticlopride, a novel substituted benzamide, selective for dopamine-D2 receptors in the rat brain.

Eur. J. Pharmacol. 111 , 191-199, (1985)

The substituted benzamide compound eticlopride, (S)-(-)-5-chloro-3-ethyl-N-[(1-ethyl-2-pyrrolidinyl) methyl]-6-methoxysalicylamide hydrochloride (FLB 131), has been shown to selectively block dopamine...

FLB 457 Hydrobromide
5-chloro-3-ethyl-2-hydroxy-6-methoxy-N-[[(2S)-1-methylpyrrolidin-2-yl]methyl]benzamide,hydrochloride
Hydrochlorofluorocarbon-131 (HCFC-131)
barium-131
cesium-131
HS-131