Chloroquinoxaline sulfonamide

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Names

[ CAS No. ]:
97919-22-7

[ Name ]:
Chloroquinoxaline sulfonamide

[Synonym ]:
Chlorsulfaquinoxaline
chloroquinoxaline sulfonamide
Sulfanilsaeure-(5-chlor-chinoxalin-2-ylamid)
4-Amino-N-(5-chloro-2-quinoxalinyl)benzenesulfonamide
5-Chloroquinoxaline-2-sulfanilamide
sulfanilic acid-(5-chloro-quinoxalin-2-ylamide)

Chemical & Physical Properties

[ Density]:
1.569g/cm3

[ Boiling Point ]:
576.3ºC at 760mmHg

[ Molecular Formula ]:
C14H11ClN4O2S

[ Molecular Weight ]:
334.78100

[ Flash Point ]:
302.3ºC

[ Exact Mass ]:
334.02900

[ PSA ]:
106.35000

[ LogP ]:
4.40120

[ Index of Refraction ]:
1.734

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DA9467000
CHEMICAL NAME :
Benzenesulfonamide, 4-amino-N-(5-chloro-2-quinoxalinyl)-
CAS REGISTRY NUMBER :
97919-22-7
BEILSTEIN REFERENCE NO. :
0312075
LAST UPDATED :
199612
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C14-H11-Cl-N4-O2-S
MOLECULAR WEIGHT :
334.80

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
600 mg/kg
TOXIC EFFECTS :
Gastrointestinal - other changes Skin and Appendages - primary irritation (after topical exposure) Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: PB87-128658
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
607 mg/kg
TOXIC EFFECTS :
Gastrointestinal - other changes Skin and Appendages - primary irritation (after topical exposure) Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: PB87-128658
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
12 mg/kg
TOXIC EFFECTS :
Gastrointestinal - other changes Skin and Appendages - primary irritation (after topical exposure) Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: PB87-128658 ** REPRODUCTIVE DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intravenous
DOSE :
600 mg/kg
SEX/DURATION :
male 1 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Paternal Effects - testes, epididymis, sperm duct
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: PB87-128658

Safety Information

[ HS Code ]:
2935009090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 2,5-dichloroquinoxaline
  • 1,2-Diamino-3-chlorobenzene
  • 4-Acetamidobenzenesulfonyl chloride

DownStream

Customs

[ HS Code ]: 2935009090

[ Summary ]:
2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%

Related Compounds

  • Chloromethane sulfonamide
  • homocysteine sulfonamide
  • Cyclohexane sulfonamide(7CI,8CI,9CI)
  • Glimepiride sulfonamide
  • hydrazine sulfonamide
  • Cresidine sulfonamide
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • methyl N-[(2-ethylphenyl)carbamothioyl]carbamate
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • Tert-butyl 2-amino-3-(3-fluoro-4-hydroxyphenyl)propanoate
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine